【摘 要】：目的 探讨幽门螺杆菌相关性胃溃疡患者治疗时采取雷贝拉唑四联疗法的临床效果。方法 研究对象选取我院消化内科收治的120例患者，均经检查确诊为幽门螺杆菌相关性胃溃疡，依据红蓝球随机法分成观察组(雷贝拉唑四联疗法)与对照组(奥美拉唑四联疗法)，对比两组患者治疗恢复情况、不良反应发生情况。结果 观察组患者治疗效果优于对照组患者、不良反应发生率低于对照组患者，组间对比差异显著(P<0.05)。结论 幽门螺杆菌相关性胃溃疡患者治疗时采取雷贝拉唑四联疗法，可以加快胃部溃疡面愈合，降低治疗时不良反应率，提高幽门螺杆菌的消除率，具有较高的临床应用价值。

    【关键词】：雷贝拉唑;奥美拉唑;幽门螺杆菌

    Abstract： objective to investigate the clinical effect of trabecazole quadruple therapy in the treatment of Helicobacter pylori associated gastric ulcer. Methods 120 patients admitted to the Department of digestive medicine in our hospital were all diagnosed with Helicobacter pylori associated gastric ulcer. They were divided into observation group(rebeprazole quadruple therapy) and control group(omeprazole quadruple therapy) according to the random red and blue globular method.) ......