放射性碘(131I)联合小剂量甲巯咪唑治疗甲亢性心脏病的临床价值分析(1)
【摘 要】目的：分析放射性碘(131I)聯合小剂量甲巯咪唑治疗甲亢性心脏病的临床价值分析。方法：选取2016年3月到2019年3月入我院门诊治疗的50例甲亢性心脏病患者作为案例进行对比研究。以随机数字法方式进行分组。常规组应用小剂量甲巯咪唑进行治疗，实验组在常规组基础上添加放射性碘131I进行治疗。总结并对比两组患者的转复率、并发症发生率、治疗前后心功能以及甲状腺功能。结果：实验组患者的转复率以及并发症发生率均显著优于常规组，组间对比结果明显，满足统计学意义标准，各项数据对比结果均有意义(P<0.05)。治疗前两组患者的心功能差异不突出，对比结果无意义(P>0.05);通过不同方案治疗后，实验组患者的心功能均显著优于常规组，组间对比结果明显，满足统计学意义标准，各项数据对比结果均有意义(P<0.05)。治疗前两组患者的各项甲状腺功能数据差异不突出，对比结果无意义(P>0.05);通过不同方案治疗后，实验组患者的各项甲状腺功能指标均显著优于常规组，组间对比结果明显，满足统计学意义标准，各项数据对比结果均有意义(P<0.05);实验组1例出现肝损伤，发生率3.33%;常规组2例出现乏力、2例出现关节疼痛、3例出现肝损伤，发生率23.33%，，组间对比结果明显，满足统计学意义标准(P<0.05)。结论：放射性碘(131I)联合小剂量甲巯咪唑治疗甲亢性心脏病的临床价值显著，能够有效改善患者的心功能，恢复甲状腺功能，能够有效提高患者的康复效益，值得在临床推广。
【关键词】放射性碘;小剂量甲巯咪唑;甲亢性心脏病;联合干预;临床价值
Abstract Objective： To analyze the clinical value of radioactive iodine (131I) combined with low-dose methimazole in the treatment of hyperthyroidism. Methods： A total of 50 patients with hyperthyroidism who were admitted to our hospital from March 2016 to March 2019 were selected as a case study. Grouping by random number method. The conventional group was treated with low-dose methimazole， and the experimental group was treated with radioactive iodine 131I on the basis of the conventional group. The conversion rate， complication rate， cardiac function and thyroid function before and after treatment were compared and compared between the two groups. Results： The conversion rate and complication rate of the experimental group were significantly better than those of the conventional group. The comparison between the groups was significant， and the statistical significance criteria were met. The comparison results of the data were significant (P<0.05). The difference of cardiac function between the two groups was not prominent before treatment， and the comparison results were not significant (P>0.05). After treatment with different regimens， the heart function of the experimental group was significantly better than that of the conventional group. The comparison between the groups was obvious and the statistics were satisfied. The meaning of the criteria， the results of the data comparison were significant (P <0.05). The differences of thyroid function data between the two groups before treatment were not prominent， and the comparison results were not significant (P>0.05). After treatment with different regimens， the thyroid function indexes of the experimental group were significantly better than the conventional group. The results were obvious， and the statistical significance criteria were met. The comparison results of all the data were significant (P<0.05). In the experimental group， 1 case of liver injury occurred， the incidence rate was 3.33%; in the conventional group， 2 cases showed fatigue， 2 cases showed joint pain， 3 There was liver injury， the incidence rate was 23.33%， and the comparison between groups was significant， which met the statistical significance (P<0.05). Conclusion： The clinical value of radioactive iodine (131I) combined with low-dose methimazole in the treatment of hyperthyroid heart disease is significant， can effectively improve the heart function of patients， restore thyroid function， can effectively improve the rehabilitation benefits of patients， and is worthy of clinical promotion., http://www.100md.com(薛秀青)
【关键词】放射性碘;小剂量甲巯咪唑;甲亢性心脏病;联合干预;临床价值
Abstract Objective： To analyze the clinical value of radioactive iodine (131I) combined with low-dose methimazole in the treatment of hyperthyroidism. Methods： A total of 50 patients with hyperthyroidism who were admitted to our hospital from March 2016 to March 2019 were selected as a case study. Grouping by random number method. The conventional group was treated with low-dose methimazole， and the experimental group was treated with radioactive iodine 131I on the basis of the conventional group. The conversion rate， complication rate， cardiac function and thyroid function before and after treatment were compared and compared between the two groups. Results： The conversion rate and complication rate of the experimental group were significantly better than those of the conventional group. The comparison between the groups was significant， and the statistical significance criteria were met. The comparison results of the data were significant (P<0.05). The difference of cardiac function between the two groups was not prominent before treatment， and the comparison results were not significant (P>0.05). After treatment with different regimens， the heart function of the experimental group was significantly better than that of the conventional group. The comparison between the groups was obvious and the statistics were satisfied. The meaning of the criteria， the results of the data comparison were significant (P <0.05). The differences of thyroid function data between the two groups before treatment were not prominent， and the comparison results were not significant (P>0.05). After treatment with different regimens， the thyroid function indexes of the experimental group were significantly better than the conventional group. The results were obvious， and the statistical significance criteria were met. The comparison results of all the data were significant (P<0.05). In the experimental group， 1 case of liver injury occurred， the incidence rate was 3.33%; in the conventional group， 2 cases showed fatigue， 2 cases showed joint pain， 3 There was liver injury， the incidence rate was 23.33%， and the comparison between groups was significant， which met the statistical significance (P<0.05). Conclusion： The clinical value of radioactive iodine (131I) combined with low-dose methimazole in the treatment of hyperthyroid heart disease is significant， can effectively improve the heart function of patients， restore thyroid function， can effectively improve the rehabilitation benefits of patients， and is worthy of clinical promotion., http://www.100md.com(薛秀青)