观察养阴益气活血汤治疗早期糖尿病肾病的临床疗效(1)
[摘要] 目的 探究治疗早期糖尿病肾病采用养阴益气活血汤的临床疗效。 方法 择取早期糖尿病肾病患者80例进行研究，80例患者均于该院2015年6月—2017年6月期间收治，以数字法进行随机分组，分为参照组40例和研究组40例，参照组接受常规西药治疗，研究组在常规治疗基础上加用养阴益气活血汤治疗，比较两组治疗效果。 结果 组间比较治疗后的效果，研究组总有效率比参照组显著更高(P>0.05)；组间比较治疗前后各实验室指标，治疗前两组血肌酐(SCr)、空腹血糖(FBG)、24 h尿清蛋白排泄率(UAER)及尿素氮(BUN)水平比较差异无统计学意义(P>0.05)，而治疗后研究组SCr、UAER水平改善程度均比参照组明显更优(P<0.05)。 结论 临床治疗早期糖尿病肾病采用养阴益气活血汤能够有效提高临床疗效，促进SCr、UAER水平降低，值得推广使用。
[关键词] 养阴益气活血汤；早期糖尿病肾病；临床疗效
[中图分类号] R59 [文献标识码] A [文章编号] 1672-4062(2017)09(a)-0001-02
Observation on Clinical Curative Effect of Yangyin Yiqi Huoxue Decoction in Treatment of Early Diabetic Kidney Disease
LYU Juan
Herb Teaching and Research Room， Shaanxi University of Traditional Chinese Medicine， Xi’an， Shanxi Province， 710000 China
[Abstract] Objective To study the clinical curative effect of yangyin yiqi huoxue Decoction in treatment of early Diabetic kidney disease. Methods 80 cases of patients with diabetic kidney disease in our hospital from June 2015 to June 2017 were selected and randomly divided into two groups with 40 cases in each， the control group adopted the routine western medicine， while the research group adopted the yangyin yiqi huoxue decoction on the basis of the routine treatment， and the treatment effect was compared between the two groups. Results After treatment， the total effective rate in the research group was obviously higher than that in the control group(P>0.05)， and the differences in the SCr， FBG， UAER， BUN levels between the two groups were not statistically significant(P>0.05)， after treatment， the improvement degrees of SCr and UAER levels in the research group were obviously better than those in the control group(P<0.05). Conclusion The yangyin yiqi huoxue decoction in clinical treatment of early diabetic kidney disease can effectively improve the clinical curative effect and promote the decrease of SCr and UAER levels， which is worth promotion and application.
[Key words] Yangyin yiqi huoxue decoction； Early diabetic kidney disease； Clinical curative effect
糖尿病肾病是糖尿病引发的一種严重、危害性十分大的慢性并发症，其特点是微血管病变导致的肾小球硬化，许多糖尿病患者死亡都是此病引起，临床对糖尿病肾病及早发现治疗对患者的病情缓解有重要意义，同时有助于使治疗的效果得到提高[1]。临床对于早期糖尿病肾病治疗的研究从未懈怠，常规西医治疗的效果并不是非常理想，且不良反应较大，因此临床开始对中医药治疗进行探索。近年来养阴益气活血汤在早期糖尿病肾病的治疗上取得了显著效果，该研究选取2015年6月—2017年6月收治的80例患者为研究对象，亦对其展开探讨，以进一步证实，现报道如下。
1 资料与方法
1.1 一般资料
择取早期糖尿病肾病患者80例进行研究，80例患者均为该院收治，所有患者均符合早期糖尿病肾病的相关诊断标准，该次研究经院伦理委员会批准后开展。以数字法进行随机分组，分为参照组40例和研究组40例。研究组患者中男性22例，女性18例；年龄37～68岁，平均(42.9±5.6)岁；病程5～11年，平均(7.2±1.4)年；参照组患者中男性23例，女性17例；年龄36～67岁，平均(42.6±5.1)岁；病程5～10年，平均(7.1±1.2)年。组间在性别、年龄、病程等资料上比较差异无统计学意义(P>0.05)。, 百拇医药(吕娟)
[关键词] 养阴益气活血汤；早期糖尿病肾病；临床疗效
[中图分类号] R59 [文献标识码] A [文章编号] 1672-4062(2017)09(a)-0001-02
Observation on Clinical Curative Effect of Yangyin Yiqi Huoxue Decoction in Treatment of Early Diabetic Kidney Disease
LYU Juan
Herb Teaching and Research Room， Shaanxi University of Traditional Chinese Medicine， Xi’an， Shanxi Province， 710000 China
[Abstract] Objective To study the clinical curative effect of yangyin yiqi huoxue Decoction in treatment of early Diabetic kidney disease. Methods 80 cases of patients with diabetic kidney disease in our hospital from June 2015 to June 2017 were selected and randomly divided into two groups with 40 cases in each， the control group adopted the routine western medicine， while the research group adopted the yangyin yiqi huoxue decoction on the basis of the routine treatment， and the treatment effect was compared between the two groups. Results After treatment， the total effective rate in the research group was obviously higher than that in the control group(P>0.05)， and the differences in the SCr， FBG， UAER， BUN levels between the two groups were not statistically significant(P>0.05)， after treatment， the improvement degrees of SCr and UAER levels in the research group were obviously better than those in the control group(P<0.05). Conclusion The yangyin yiqi huoxue decoction in clinical treatment of early diabetic kidney disease can effectively improve the clinical curative effect and promote the decrease of SCr and UAER levels， which is worth promotion and application.
[Key words] Yangyin yiqi huoxue decoction； Early diabetic kidney disease； Clinical curative effect
糖尿病肾病是糖尿病引发的一種严重、危害性十分大的慢性并发症，其特点是微血管病变导致的肾小球硬化，许多糖尿病患者死亡都是此病引起，临床对糖尿病肾病及早发现治疗对患者的病情缓解有重要意义，同时有助于使治疗的效果得到提高[1]。临床对于早期糖尿病肾病治疗的研究从未懈怠，常规西医治疗的效果并不是非常理想，且不良反应较大，因此临床开始对中医药治疗进行探索。近年来养阴益气活血汤在早期糖尿病肾病的治疗上取得了显著效果，该研究选取2015年6月—2017年6月收治的80例患者为研究对象，亦对其展开探讨，以进一步证实，现报道如下。
1 资料与方法
1.1 一般资料
择取早期糖尿病肾病患者80例进行研究，80例患者均为该院收治，所有患者均符合早期糖尿病肾病的相关诊断标准，该次研究经院伦理委员会批准后开展。以数字法进行随机分组，分为参照组40例和研究组40例。研究组患者中男性22例，女性18例；年龄37～68岁，平均(42.9±5.6)岁；病程5～11年，平均(7.2±1.4)年；参照组患者中男性23例，女性17例；年龄36～67岁，平均(42.6±5.1)岁；病程5～10年，平均(7.1±1.2)年。组间在性别、年龄、病程等资料上比较差异无统计学意义(P>0.05)。, 百拇医药(吕娟)