曼月乐对糖尿病妇女血糖的影响与避孕效果观察(1)
[摘要] 目的 探讨曼月乐对糖尿病妇女血糖的影响与避孕的效果。方法 选取该科2017年1月—2018年1月收治的放置节育器的糖尿病妇女112例，随机分为两组各56例，观察组放置曼月乐环，对照组放置含铜节育环，比较效果。结果 放置后观察组FPG(6.6±0.6)mmol/L、2 hPG(8.6±1.5)mmol/L与对照组比较差异无统计学意义(P>0.05)；观察组避孕有效率为96.4%，显著高于对照组89.3%(P<0.05)，观察组不良反应发生率为5.4%，显著低于对照组23.2%(P<0.05)。结论 宫内放置曼月乐避孕效果好，且对血糖无影响，是糖尿病妇女有效的避孕措施。
[关键词] 曼月乐；血糖；避孕
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2018)06(b)-0079-02
Effect of Mirena on Blood Glucose in Diabetic Women and Observation of Contraceptive Effect
DONG Jian-hua
Family Planning Department， Changchun Maternity Hospital， Changchun， Jilin Province， 130000 China
[Abstract] Objective To investigate the effect of Mirena on blood glucose in diabetic women and the effect of contraception. Methods A total of 112 diabetic women with IUDs were enrolled in the department from January 2017 to January 2018. They were randomly divided into two groups， 56 cases. The observation group was placed in the Mirena ring， and the control group was placed in the copper-containing ring. effect. Results After placement， the FPG(6.6±0.6)mmol/L and 2 hPG (8.6±1.5) mmol/L in the observation group were not significantly different from the control group (P>0.05). The effective rate of contraception in the observation group was 96.4%， which was significantly higher than that in the observation group. The control group was 89.3% (P<0.05). The incidence of adverse reactions in the observation group was 5.4%， which was significantly lower than that in the control group (23.2%) (P<0.05). Conclusion Intrauterine placement of Mirena is effective and has no effect on blood glucose. It is an effective contraceptive measure for women with diabetes.
[Key words] Mirena； Blood glucose； Contraception
糖尿病是臨床常见的代谢性疾病。近年来，因各种不良因素的影响，女性患糖尿病的比例不断升高，严重影响了广大女性的身心健康，同时也增加了妊娠风险[1]。宫内节育器是目前妇女最常用的避孕技术，全世界有约1.5亿妇女通过宫内放置节育器的方式避孕[2]。节育器的放置虽能起到良好的避孕效果，但不同的节育器避孕效果不一，放置后引起的不良反应也大不相同。为探讨不同节育器的避孕效果和对血糖的影响，该科对2017年1月—2018年1月收治的放置节育器的112例糖尿病妇女进行观察，分别放置曼月乐环和含铜节育环，并比较效果，现报道如下。
1 资料与方法
1.1 一般资料
选取该科收治的放置节育器的糖尿病妇女112例为研究对象，随机分为两组各56例，观察组年龄25～41岁，平均(31.2±2.4)岁，孕次1～5次，产次0～3次，糖尿病病程3～9年，平均(5.6±1.0)年，放置时间：人工流产后立即放置20例，术后或产后月经来潮后1～3个月放置36例；对照组年龄24～40岁，平均(30.7±2.1)岁，孕次1～5次，产次0～3次，糖尿病病程3～8.4年，平均(5.1±1.2)年，放置时间：人工流产后立即放置22例，术后或产后月经来潮后1～3个月放置34例。该组女性均自愿要求放置节育环进行避孕并经伦理委员会批准，排除生殖道肿瘤、宫颈口松弛、子宫畸形等放置节育器禁忌证者。两组妇女一般资料比较差异无统计学意义(P>0.05)。
1.2 方法
妇女放置节育器前后均控制血糖。观察组：于月经来潮后3～7 d宫内放置曼月乐(左炔诺孕酮宫内节育系统，国药准字J20140088)。对照组：于月经来潮后3～7 d宫内放置含铜节育环。放置过程中注意无菌操作，放置后口服抗生素3 d预防感染。, http://www.100md.com(董建华)
[关键词] 曼月乐；血糖；避孕
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2018)06(b)-0079-02
Effect of Mirena on Blood Glucose in Diabetic Women and Observation of Contraceptive Effect
DONG Jian-hua
Family Planning Department， Changchun Maternity Hospital， Changchun， Jilin Province， 130000 China
[Abstract] Objective To investigate the effect of Mirena on blood glucose in diabetic women and the effect of contraception. Methods A total of 112 diabetic women with IUDs were enrolled in the department from January 2017 to January 2018. They were randomly divided into two groups， 56 cases. The observation group was placed in the Mirena ring， and the control group was placed in the copper-containing ring. effect. Results After placement， the FPG(6.6±0.6)mmol/L and 2 hPG (8.6±1.5) mmol/L in the observation group were not significantly different from the control group (P>0.05). The effective rate of contraception in the observation group was 96.4%， which was significantly higher than that in the observation group. The control group was 89.3% (P<0.05). The incidence of adverse reactions in the observation group was 5.4%， which was significantly lower than that in the control group (23.2%) (P<0.05). Conclusion Intrauterine placement of Mirena is effective and has no effect on blood glucose. It is an effective contraceptive measure for women with diabetes.
[Key words] Mirena； Blood glucose； Contraception
糖尿病是臨床常见的代谢性疾病。近年来，因各种不良因素的影响，女性患糖尿病的比例不断升高，严重影响了广大女性的身心健康，同时也增加了妊娠风险[1]。宫内节育器是目前妇女最常用的避孕技术，全世界有约1.5亿妇女通过宫内放置节育器的方式避孕[2]。节育器的放置虽能起到良好的避孕效果，但不同的节育器避孕效果不一，放置后引起的不良反应也大不相同。为探讨不同节育器的避孕效果和对血糖的影响，该科对2017年1月—2018年1月收治的放置节育器的112例糖尿病妇女进行观察，分别放置曼月乐环和含铜节育环，并比较效果，现报道如下。
1 资料与方法
1.1 一般资料
选取该科收治的放置节育器的糖尿病妇女112例为研究对象，随机分为两组各56例，观察组年龄25～41岁，平均(31.2±2.4)岁，孕次1～5次，产次0～3次，糖尿病病程3～9年，平均(5.6±1.0)年，放置时间：人工流产后立即放置20例，术后或产后月经来潮后1～3个月放置36例；对照组年龄24～40岁，平均(30.7±2.1)岁，孕次1～5次，产次0～3次，糖尿病病程3～8.4年，平均(5.1±1.2)年，放置时间：人工流产后立即放置22例，术后或产后月经来潮后1～3个月放置34例。该组女性均自愿要求放置节育环进行避孕并经伦理委员会批准，排除生殖道肿瘤、宫颈口松弛、子宫畸形等放置节育器禁忌证者。两组妇女一般资料比较差异无统计学意义(P>0.05)。
1.2 方法
妇女放置节育器前后均控制血糖。观察组：于月经来潮后3～7 d宫内放置曼月乐(左炔诺孕酮宫内节育系统，国药准字J20140088)。对照组：于月经来潮后3～7 d宫内放置含铜节育环。放置过程中注意无菌操作，放置后口服抗生素3 d预防感染。, http://www.100md.com(董建华)