Cys-C、hs-CRP、TRF联合检测应用于糖尿病肾病早期诊断价值研究(1)
[摘要] 目的 研究应用Cys-C、hs-CRP、TRF联合检测早期糖尿病肾病的诊断价值。 方法 选取2017年3月—2018年3月间来该院接受治疗的早期糖尿病肾病患者30例作为该次研究的实验对象，称为早期DN组;同时在同时间段在该院接受治疗的糖尿病患者中挑选30例患者参与这次的实验研究，称为单纯DM组;另外在同时期选30名健康人群作为对照组，3组都同时检测Cys-C、hs-CRP以及TRF的相关水平，观察其检测结果并对其做出评价。结果 经过实验研究可知，单纯DM组和早期DN组的Cys-C、hs-CRP水平都要明显高于对照组，TRF水平要明显低于对照组(P<0.05);而且早期DN组的Cys-C、hs-CRP水平还要显著高于单纯DM组，TRF水平要明显低于DM组(P<0.05)。另外还可以知道，在早期DN组患者的检测中，联合检测的检出率要显著高于单项检出率，差异有统计学意义(P<0.05)。结论 由此可知，应用Cys-C、hs-CRP、TRF联合检测早期糖尿病肾病可以为疾病的诊断提供依据，让患者做到及早诊断，及早治疗，是检测早期糖尿病肾病的重要指标，因此，可以在临床检测中大力推广。
[关键词] Cys-C;hs-CRP;TRF;早期糖尿病肾病;价值研究
[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062(2019)01(b)-0008-03
[Abstract] Objective To study the diagnostic value of combined detection of Cys-C， hs-CRP and TRF in early diabetic nephropathy. Methods 30 patients with early diabetic nephropathy who were treated in our hospital from March 2017 to March 2018 were selected as the experimental subjects of this study， which were called early DN group. At the same time， in our hospital， 30 patients were selected to participate in this experimental study， referred to as the DM group alone. In addition， 30 healthy people were selected as the control group at the same time， and the three groups were simultaneously tested for the relevant levels of Cys-C， hs-CRP and TRF. Observe the results of the test and evaluate it. Results According to the experimental study， the levels of Cys-C and hs-CRP in the DM group and the early DN group were significantly higher than those in the control group， and the TRF level was significantly lower than that in the control group(P<0.05); and Cys-C and hs-CRP in the early DN group were significantly higher than those of the DM group alone. The TRF level was significantly lower than that of the DM group (P<0.05). In addition， it can be known that in the early detection of DN patients， the detection rate of combined detection was significantly higher than the single detection rate， the difference was statistically significant(P<0.05). Conclusion It can be seen that the combination of Cys-C， hs-CRP and TRF to detect early diabetic nephropathy can provide a basis for the diagnosis of the disease， allowing patients to diagnose early and treat early. It is an important indicator for detecting early diabetic nephropathy， which can be greatly promoted in clinical testing.
[Key words] Cys-C; hs-CRP; TRF; Early diabetic nephropathy; Value study
糖尿病腎病是糖尿病患者最重要的合并症之一，也是导致糖尿病患者死亡的原因之一，在我国的发病率正在逐年上升，因此早期发现早期治疗将会极大的降低患者的死亡率[1-2]。糖尿病肾病的患者临床症状主要表现为蛋白尿，很多患者由于对病情不了解，马虎大意，没有及时就诊，诊断不清或者出现漏诊的情况，使患者的治疗不及时，延误了最佳治疗时机，就会造成患者的肾功能出现异常，严重者可导致患者出现肾功能的衰竭，危及患者的生命财产安全[3]。因此，对早期糖尿病肾病进行早期的诊断是非常有必要的，临床上就是对患者的Cys-C、hs-CRP以及TRF进行检测来判定患者是否出现早期糖尿病肾病，经验证，Cys-C、hs-CRP以及TRF联合检测已取得了相当不错的成绩，该文以2017年3月—2018年3月收治的90例患者为研究对象，这次实验研究也是对这一论点进行再论证，报道如下。, 百拇医药(葛明广)
[关键词] Cys-C;hs-CRP;TRF;早期糖尿病肾病;价值研究
[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062(2019)01(b)-0008-03
[Abstract] Objective To study the diagnostic value of combined detection of Cys-C， hs-CRP and TRF in early diabetic nephropathy. Methods 30 patients with early diabetic nephropathy who were treated in our hospital from March 2017 to March 2018 were selected as the experimental subjects of this study， which were called early DN group. At the same time， in our hospital， 30 patients were selected to participate in this experimental study， referred to as the DM group alone. In addition， 30 healthy people were selected as the control group at the same time， and the three groups were simultaneously tested for the relevant levels of Cys-C， hs-CRP and TRF. Observe the results of the test and evaluate it. Results According to the experimental study， the levels of Cys-C and hs-CRP in the DM group and the early DN group were significantly higher than those in the control group， and the TRF level was significantly lower than that in the control group(P<0.05); and Cys-C and hs-CRP in the early DN group were significantly higher than those of the DM group alone. The TRF level was significantly lower than that of the DM group (P<0.05). In addition， it can be known that in the early detection of DN patients， the detection rate of combined detection was significantly higher than the single detection rate， the difference was statistically significant(P<0.05). Conclusion It can be seen that the combination of Cys-C， hs-CRP and TRF to detect early diabetic nephropathy can provide a basis for the diagnosis of the disease， allowing patients to diagnose early and treat early. It is an important indicator for detecting early diabetic nephropathy， which can be greatly promoted in clinical testing.
[Key words] Cys-C; hs-CRP; TRF; Early diabetic nephropathy; Value study
糖尿病腎病是糖尿病患者最重要的合并症之一，也是导致糖尿病患者死亡的原因之一，在我国的发病率正在逐年上升，因此早期发现早期治疗将会极大的降低患者的死亡率[1-2]。糖尿病肾病的患者临床症状主要表现为蛋白尿，很多患者由于对病情不了解，马虎大意，没有及时就诊，诊断不清或者出现漏诊的情况，使患者的治疗不及时，延误了最佳治疗时机，就会造成患者的肾功能出现异常，严重者可导致患者出现肾功能的衰竭，危及患者的生命财产安全[3]。因此，对早期糖尿病肾病进行早期的诊断是非常有必要的，临床上就是对患者的Cys-C、hs-CRP以及TRF进行检测来判定患者是否出现早期糖尿病肾病，经验证，Cys-C、hs-CRP以及TRF联合检测已取得了相当不错的成绩，该文以2017年3月—2018年3月收治的90例患者为研究对象，这次实验研究也是对这一论点进行再论证，报道如下。, 百拇医药(葛明广)