[摘要] 目的 探讨伊立替康联合替吉奥治疗糖尿病合并晚期结肠癌的效果。方法 选取该科2017年9月—2018年9月收治的糖尿病合并晚期结肠癌患者74例，随机分为两组，各37例，对照组采用替吉奥治疗，观察组采用伊立替康联合替吉奥治疗。结果 观察组有效率为59.5%，显著高于对照组43.2%，差异有统计学意义(P<0.05);治疗后观察组FPG、2 hPG显著低于对照组，差异有统计学意义(P<0.05)。 结论 糖尿病合并晚期结肠癌患者采用伊立替康联合替吉奥治疗效果显著，利于控制血糖。

    [关键词] 伊立替康替吉奥;糖尿病;晚期结肠癌

    [中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2019)07(b)-0067-02

    [Abstract] Objective To investigate the effect of irinotecan combined with tegafur in the treatment of diabetes with advanced colon cancer. Methods A total of 74 patients with diabetes mellitus and advanced colon cancer admitted to our department from September 2017 to September 2018 were randomly divided into two groups： 37 patients each. The control group was treated with tigeo. The observation group was treated with irinotecan and thiopyrol treatment. Results The effective rate of the observation group was 59.5% ......