[摘要] 目的 分析2型糖尿病合并甲亢患者骨密度(BMD)及骨代谢的特点。方法 2018年1月—2019年1月，选择68例2型糖尿病合并甲亢患者作为观察组，另选同期68例甲状腺功能正常的2型糖尿病患者作为对照组;比较两组不同部位BMD、骨代谢指标及血糖控制效果。结果 观察组不同部位BMD均明显小于对照组，血清25(OH)D、BGP、TPⅠNP水平均明显低于对照组，β-CTX水平均明显高于对照组，差异有统计学意义(P<0.05);观察组治疗后FBG、2 hPBG、HbA1c水平均明显低于对照组，差异有统计学意义(P<0.05)。结论 2型糖尿病患者合并甲亢可进一步增加骨吸收，降低骨形成，影响血糖控制效果。

    [关键词] 2型糖尿病;甲亢;骨密度;骨代谢

    [中图分类号] R587.1;R581.1 [文献标识码] A [文章编号] 1672-4062(2019)10(b)-0044-02

    [Abstract] Objective To analyze the characteristics of bone mineral density(BMD) and bone metabolism in patients with type 2 diabetes mellitus complicated with hyperthyroidism. Methods 68 patients with type 2 diabetes mellitus complicated with hyperthyroidism from January 2018 to January 2019 were selected as the observation group. 68 patients with type 2 diabetes mellitus with normal thyroid function were selected as the control group. BMD ......