东北地区糖尿病患者皮肤病患病情况及相关危险因素分析(1)
[摘要] 目的 分析东北地区糖尿病患者皮肤病患病情况及相关危险因素。方法 该研究抽选东北地区113例糖尿病住院患者作为观察对象，样本抽选时间为2018年6月—2019年6月期间。回顾性分析上述患者的临床病历资料，掌握其皮肤病患病情况，并且分析导致糖尿病患者发生皮肤病的相关危险因素。结果 其中真菌感染占比>湿疹炎占比>细菌感染占比>瘙痒症占比>荨麻疹占比>非念珠菌性擦烂红斑占比>皮赘占比与黄皮肤占比>胫前色素斑占比>过敏性紫癜占比与皮肤淀粉样变性占比，经多因素非条件Logistic回归分析发现，东北地区糖尿病患者发生皮肤病同糖尿病并发症、高血压以及血脂异常因素之间有密切关联。结论 东北地区糖尿病患者皮肤病主要以真菌感染为主，高血压、血脂异常以及糖尿病并发症为导致患者出现皮肤病的重要危险因素。
[关键词] 东北地区;糖尿病;皮肤病;患病率;相关危险因素
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2020)07(a)-0037-03
Analysis of Prevalence of Dermatosis and Related Risk Factors in Diabetic Patients in Northeast China
XING Rong-gui， LIU Bing-mei， XIA Li-jie， CHENG Xue， GUO Ya-nan
Department of Dermatology， Heilongjiang Provincial Hospital， Harbin， Heilongjiang Province， 150000 China
[Abstract] Objective To analyze the prevalence of dermatosis and related risk factors in diabetic patients in Northeast China. Methods This study selected 113 inpatients with diabetes in Northeast China as observation objects. The sample selection period was from June 2018 to June 2019. Retrospectively analyze the clinical data of the above patients， grasp the prevalence of their skin diseases， and analyze the related risk factors that lead to skin diseases in diabetic patients. Results Among them， Proportion of fungal infection proportion of > eczematitis proportion of > bacterial infection proportion of > pruritus proportion of > urticaria proportion of > proportion of erythema caused by non-candida abrasives proportion of > dermatophytosis proportion of > proportion of tibial pretibial pigmentation proportion of > proportion of allergic purpura proportion of > proportion of skin amyloidosis proportion， after multi-factor unconditional logistic regression analysis， it was found that there was a close relationship between the occurrence of skin disease and diabetes complications， hypertension and dyslipidemia in diabetic patients in Northeast China associated. Conclusion The skin diseases of diabetic patients in Northeast China are mainly fungal infections. Hypertension， dyslipidemia and diabetic complications are important risk factors for patients with skin diseases.
[Key words] Northeast China; Diabetes; Skin disease; Prevalence; Related risk factors
糖尿病為目前临床中发病率较高的慢性终身代谢性疾病，近年来该疾病的临床发病率随着人们生活与饮食习惯的改变明显提升，成为威胁人类身体健康以及生活质量的慢性病变之一[1]。糖尿病常伴随多种皮肤损害，可对患者正常的生活和工作产生严重不良影响。糖尿病患者患皮肤病可能同外周血长时间处于高血糖的状态下导致蛋白质出现糖基化，使得微血管以及皮肤胶原蛋白结构与功能发生改变，进而诱发各类皮肤疾病，此外患者的机体长时间处于高血糖的状态，影响白细胞的功能，且可以减少抗体与补体的产生量，进而损伤机体的免疫系统，提升各类感染的发生率[2]。该文于2018年6月—2019年6月选取113例患者，主要分析东北地区糖尿病患者的皮肤病患病情况以及导致皮肤病发生的相关危险因素，旨在为今后临床疾病治疗与防控提供参考，现报道如下。, 百拇医药(邢荣贵 刘冰梅 夏立杰 程雪 郭亚南)
[关键词] 东北地区;糖尿病;皮肤病;患病率;相关危险因素
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2020)07(a)-0037-03
Analysis of Prevalence of Dermatosis and Related Risk Factors in Diabetic Patients in Northeast China
XING Rong-gui， LIU Bing-mei， XIA Li-jie， CHENG Xue， GUO Ya-nan
Department of Dermatology， Heilongjiang Provincial Hospital， Harbin， Heilongjiang Province， 150000 China
[Abstract] Objective To analyze the prevalence of dermatosis and related risk factors in diabetic patients in Northeast China. Methods This study selected 113 inpatients with diabetes in Northeast China as observation objects. The sample selection period was from June 2018 to June 2019. Retrospectively analyze the clinical data of the above patients， grasp the prevalence of their skin diseases， and analyze the related risk factors that lead to skin diseases in diabetic patients. Results Among them， Proportion of fungal infection proportion of > eczematitis proportion of > bacterial infection proportion of > pruritus proportion of > urticaria proportion of > proportion of erythema caused by non-candida abrasives proportion of > dermatophytosis proportion of > proportion of tibial pretibial pigmentation proportion of > proportion of allergic purpura proportion of > proportion of skin amyloidosis proportion， after multi-factor unconditional logistic regression analysis， it was found that there was a close relationship between the occurrence of skin disease and diabetes complications， hypertension and dyslipidemia in diabetic patients in Northeast China associated. Conclusion The skin diseases of diabetic patients in Northeast China are mainly fungal infections. Hypertension， dyslipidemia and diabetic complications are important risk factors for patients with skin diseases.
[Key words] Northeast China; Diabetes; Skin disease; Prevalence; Related risk factors
糖尿病為目前临床中发病率较高的慢性终身代谢性疾病，近年来该疾病的临床发病率随着人们生活与饮食习惯的改变明显提升，成为威胁人类身体健康以及生活质量的慢性病变之一[1]。糖尿病常伴随多种皮肤损害，可对患者正常的生活和工作产生严重不良影响。糖尿病患者患皮肤病可能同外周血长时间处于高血糖的状态下导致蛋白质出现糖基化，使得微血管以及皮肤胶原蛋白结构与功能发生改变，进而诱发各类皮肤疾病，此外患者的机体长时间处于高血糖的状态，影响白细胞的功能，且可以减少抗体与补体的产生量，进而损伤机体的免疫系统，提升各类感染的发生率[2]。该文于2018年6月—2019年6月选取113例患者，主要分析东北地区糖尿病患者的皮肤病患病情况以及导致皮肤病发生的相关危险因素，旨在为今后临床疾病治疗与防控提供参考，现报道如下。, 百拇医药(邢荣贵 刘冰梅 夏立杰 程雪 郭亚南)