补虚祛浊通络法对老年2型糖尿病aMCI患者的ADAS-COG-DVR量表的影响(1)
[摘要] 目的 对患有轻度认知功能障碍、2型糖尿病的老年患者施以补虚祛浊通络治疗方法，观察该治疗方法对患者ADAS-COG-DVR量表的影响。方法 以该院2018年1月—2020年5月纳入的80例老年2型糖尿病aMCI患者为研究对象，根据治疗方式差异分为两组。其中，对照组施以常规治疗法，观察组施以补虚祛浊通络法，对比两组患者治疗前后的中医证候疗效以及患者的ADAS-Cog变化情况。结果 经对比显示，两组患者中医证候评分除腰膝酸软之外，其余差异有统计学意义(P<0.05);观察组患者治疗前后ADAS-COG-DVR量表，经对比，差异有统计学意义(P<0.05)。结论 通过该次研究可以看出，对患有轻度认知功能障碍与2型糖尿病的老年患者施以补虚祛浊通络治疗方法，有助于患者认知损害方面的治疗。
[关键词] 补虚祛浊通络法;老年2型糖尿病aMCI患者;ADAS-COG-DVR量表
[中图分类号] R4 [文献标识码] A [文章编号] 1672-4062(2020)11(a)-0069-03
[Abstract] Objective The elderly patients with mild cognitive dysfunction and type 2 diabetes were treated with a method of invigorating deficiency， removing turbidity and dredging collaterals， and observing the effect of the treatment on the ADAS-COG-DVR scale of patients. Methods 80 elderly patients with type 2 diabetes aMCI included in the hospital from January 2018 to May 2020 were divided into two groups according to the difference in treatment. Among them， the control group was treated with conventional treatment， and the observation group was treated with the method of replenishing deficiency， removing turbidity and dredging collaterals， comparing the efficacy of TCM syndromes before and after treatment and the changes in ADAS-COG of the two groups of patients. Results The comparison showed that the P values of TCM syndrome scores of patients in the two groups were， the difference was statistically significant(P<0.05) except for lumbar and knee tenderness. The ADAS-COG-DVR scale was compared before and after treatment in the observation group， and the difference was statistically significant (P<0.05). Conclusion It can be seen from this study that the treatment of elderly patients with mild cognitive impairment and type 2 diabetes with the method of supplementing deficiency， removing turbidity and clearing collateralismis helpful for the treatment of cognitive impairment.
[Key words] Buxu Quzhuo Tongluo method; Elderly patients with type 2 diabetes aMCI; ADAS-COG-DVR scale
老年2型糖尿病aMCI患者不僅在学习、记忆力等方面有着明显降低，并且其分析能力、整体智能、表达能力等方面也会出现一定程度的异常，严重影响患者的正常生活。据相关研究数据显示，与正常人相比，由于糖尿病患者存在胰岛素抵抗，因此患认知功能障碍的几率更高。近年来，随着我国糖尿病患者人数不断增多、患者年龄不断提高，老年2型糖尿病aMCI患者人数持续上涨，不仅影响其自身生活质量，并且还对患者家庭造成严重负担。糖尿病临床症状主要表现为多尿、疲乏无力和多食，慢性并发症会遍及重要器官，致使大血管和微血管出现病变，患者生活质量大幅度下降。基于此，该文对该院2018年1月—2020年5月补虚祛浊通络法在治疗80例老年2型糖尿病aMCI患者中的应用效果进行研究。现报道如下。
1 资料与方法
1.1 一般资料
以该院纳入的80例老年2型糖尿病aMCI患者为研究对象，根据治疗方式差异平均分为两组。其中，对照组施以常规治疗法，观察组施以补虚祛浊通络法。该次所选患者年龄为60～80岁，2型糖尿病病史均达5年以上，且与中医辩证分型诊断标准相符。另外，所选患者均存在轻度的认知功能障碍，入院检测CDR平均评分为0.5分、IADL评分均小于16分。简易精神状态量表(MMSE)评分，参照文化程度评定，文盲评分≥17分，小学文化程度评分≥20分，中学文化程度以上评分≥24分。经对比，两组患者一般资料差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(赵丽华 孙莉 项颗 张水生 董光)
[关键词] 补虚祛浊通络法;老年2型糖尿病aMCI患者;ADAS-COG-DVR量表
[中图分类号] R4 [文献标识码] A [文章编号] 1672-4062(2020)11(a)-0069-03
[Abstract] Objective The elderly patients with mild cognitive dysfunction and type 2 diabetes were treated with a method of invigorating deficiency， removing turbidity and dredging collaterals， and observing the effect of the treatment on the ADAS-COG-DVR scale of patients. Methods 80 elderly patients with type 2 diabetes aMCI included in the hospital from January 2018 to May 2020 were divided into two groups according to the difference in treatment. Among them， the control group was treated with conventional treatment， and the observation group was treated with the method of replenishing deficiency， removing turbidity and dredging collaterals， comparing the efficacy of TCM syndromes before and after treatment and the changes in ADAS-COG of the two groups of patients. Results The comparison showed that the P values of TCM syndrome scores of patients in the two groups were， the difference was statistically significant(P<0.05) except for lumbar and knee tenderness. The ADAS-COG-DVR scale was compared before and after treatment in the observation group， and the difference was statistically significant (P<0.05). Conclusion It can be seen from this study that the treatment of elderly patients with mild cognitive impairment and type 2 diabetes with the method of supplementing deficiency， removing turbidity and clearing collateralismis helpful for the treatment of cognitive impairment.
[Key words] Buxu Quzhuo Tongluo method; Elderly patients with type 2 diabetes aMCI; ADAS-COG-DVR scale
老年2型糖尿病aMCI患者不僅在学习、记忆力等方面有着明显降低，并且其分析能力、整体智能、表达能力等方面也会出现一定程度的异常，严重影响患者的正常生活。据相关研究数据显示，与正常人相比，由于糖尿病患者存在胰岛素抵抗，因此患认知功能障碍的几率更高。近年来，随着我国糖尿病患者人数不断增多、患者年龄不断提高，老年2型糖尿病aMCI患者人数持续上涨，不仅影响其自身生活质量，并且还对患者家庭造成严重负担。糖尿病临床症状主要表现为多尿、疲乏无力和多食，慢性并发症会遍及重要器官，致使大血管和微血管出现病变，患者生活质量大幅度下降。基于此，该文对该院2018年1月—2020年5月补虚祛浊通络法在治疗80例老年2型糖尿病aMCI患者中的应用效果进行研究。现报道如下。
1 资料与方法
1.1 一般资料
以该院纳入的80例老年2型糖尿病aMCI患者为研究对象，根据治疗方式差异平均分为两组。其中，对照组施以常规治疗法，观察组施以补虚祛浊通络法。该次所选患者年龄为60～80岁，2型糖尿病病史均达5年以上，且与中医辩证分型诊断标准相符。另外，所选患者均存在轻度的认知功能障碍，入院检测CDR平均评分为0.5分、IADL评分均小于16分。简易精神状态量表(MMSE)评分，参照文化程度评定，文盲评分≥17分，小学文化程度评分≥20分，中学文化程度以上评分≥24分。经对比，两组患者一般资料差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(赵丽华 孙莉 项颗 张水生 董光)