内源性凝血在脓毒症凝血紊乱中的作用及研究进展(6)
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[49]ZHANG H， LOWENBERG E C， CROSBY J R， et al. Inhibition of the intrinsic coagulation pathway factor Ⅺ by antisense oligonucleotides： a novel antithrombotic strategy with lowered bleeding risk[J]. Blood， 2010，116(22)：4684-4692.
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[51]XU Y M， CAI T Q， CASTRIOTA G， et al. Factor Ⅺ la inhibition by infestin-4： in vitro mode of action and in vivo antithrombotic benefit[J]. Thrombosis and Haemostasis， 2014，111(4)：694-704., 百拇医药(温菲 唐雯 靳茜茜 王焕亮)
[47]HERAULT J P， PERRIN B， JONGBLOET C， et al. Effect of factor Ⅹa inhibitors on the platelet-derived microparticles procoagulant activity in vitro and in vivo in rats[J]. Thrombosis and Haemostasis， 2000，84(4)：668-674.
[48]MULLER F， GAILANI D， RENNE T. Factor Ⅺ and Ⅻ as antithrombotic targets[J]. Current Opinion in Hematology， 2011，18(5)：349-355.
[49]ZHANG H， LOWENBERG E C， CROSBY J R， et al. Inhibition of the intrinsic coagulation pathway factor Ⅺ by antisense oligonucleotides： a novel antithrombotic strategy with lowered bleeding risk[J]. Blood， 2010，116(22)：4684-4692.
[50]KLEINSCHNITZ C， STOLL G， BENDSZUS M， et al. Targeting coagulation factor Ⅻ provides protection from patholo-
gical thrombosis in cerebral ischemia without interfering with hemostasis[J]. Journal of Experimental Medicine， 2006，203(3)：513-518.
[51]XU Y M， CAI T Q， CASTRIOTA G， et al. Factor Ⅺ la inhibition by infestin-4： in vitro mode of action and in vivo antithrombotic benefit[J]. Thrombosis and Haemostasis， 2014，111(4)：694-704., 百拇医药(温菲 唐雯 靳茜茜 王焕亮)