DHF对过氧化氢诱导H9c2心肌细胞损伤保护作用(2)
ResultsExperiment 1 showed that cell viability decreased to (54.1±5.8)% after H2O2 treatment， while 5-20 μmol/L DHF pretreatment exerted a marked protective effect on cells (n=6，F=16.50，q=1.95-4.76，P<0.05). Experiment 2 showed that H2O2 significantly downregulated the protein expression of p-Akt， while DHF pretreatment upregulated the protein expression of p-Akt， which was inhibited by the PI3K antagonist LY294002; DHF used alone had no marked effect on the phosphorylation of Akt (n=3 ......
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