[摘要] 目的 采用经食管超声心动图(TEE)观察后路腰椎椎体间融合术中静脉气体栓塞(VAE)发生率及呼气末正压通气(PEEP)对VAE发生率的影响。方法 将120例拟全麻下行后路腰椎椎体间融合术病人随机分为对照组、PEEP1组和PEEP2组，各40例。3组术中分别设置PEEP为0、0.49、0.98 kPa，同时采用TEE监测并评估各组VAE分级。结果 对照组VAE主要为Ⅰ级和Ⅱ级，PEEP1组和PEEP2组VAE主要为0级和Ⅰ级，3组VAE分级比较差异有显著性(H=30.24，Z=1.98～5.43，P<0.01)。结论 手术中PEEP可有效降低后路腰椎椎体间融合术病人VAE的发生率，提高手术安全性。

    [关键词] 脊柱融合术;栓塞，空气;正压呼吸;超声心动描记术，经食管

    [中图分类号] R614 [文献标志码] A [文章编号] 2096-5532(2020)06-0715-04

    doi：10.11712/jms.2096-5532.2020.56.175 [开放科学(资源服务)标识码(OSID)]

    [网络出版] https：//kns.cnki.net/kcms/detail/37.1517.R.20201016.1124.002.html;

    [ABSTRACT] Objective To investigate the effect of positive end-expiratory pressure (PEEP) on the incidence rate of venous air embolism (VAE) during posterior lumbar interbody fusion (PLIF) using transesophageal echocardiography (TEE). Methods A total of 120 patients who planned to undergo PLIF under general anesthesia were randomly divided into control group ......