论炎性细胞因子与脑缺血(3)
7 Liu T Dooonnell PC,yong RP,et al.Interleukin-1β mRNA expression in isvhemic eat cirtex,Sreoke,1993,24(II):1746~1751
8 SaitoK.SuyamaK Nishida L et al.Earty increases in TNA-α,IL-6,and IL-1βlevels following transient cerebral ischemia in gerbil bran.NeuroscilLett,1996,206(20:149~152
9 Liu T、Clark R、Yong PR.Tumor necrosis faaeyor in ischemic neurons.Stroke,1994,25(7):1481~1488
10 Fassbcnder K、Rossol S、Kammer T.Proinflammmtory cytokins in serum of patients with acute cerebral ischemia; kinetics of seretion and relation to extent of brain damage and outcme of disease,JNeuurol Sci,1998,126(3):135~139
11 Tarkowski E\Roengren L\Blomstrand C、et al.Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke,2000,31(8)1393~1340
12 Dewson DA、Martion.D.Hallcnbeck JM.Inhibition of tumor necrosis factior-alpha redues focal cerebral ischemic injury in the spontaneously hypertensive rat.Neurosci lett.1996,218(10:41~44
13 Rothwell NL、Hopkis SJ.Cytokies and nercous system Ⅱ:actions and mechanisms of action Trends Neurosci，2001，2223(3):331~339
14 Merrill JE,Benveniste EN,Cytokinos in inflammatory brain lesions:helpful and harmful.TINS,1996,21(18):331~339
15 Yamade M,Hatanaka H,interieukin-6protects culture rat hippicamoral neurons againsr glutamatc-induced cell death Brain Res，1999,648(4):173
16 CampbellIL、Abrahan CR、Masliah E、et al.Neurotogic induced in reansgenjc mice by cerebral overexpression of interieukin-6.Proc Natl Sci USA,1999,96(14):10061~10065
17 YamasakiY,Masuura N Shozuhara Het al Interleykin-1 as a pathogeneti mediator of ischemic brain damage in rats.Stroke,1995,25(4):676~682
18 HaraH、Friedlander Rm、Gagliaedini Vet al Inhibition of interleukin-Ibeta coinvertion enzyme family proteases reduces ischemic and exciririxic neuronal damage.Proc Ncad Sci USA，1997,94(5):2007~2012
19 Loddick SA、Mackcnzic a.Rothwell NJ An ICE inhibitur ZVAD-DCB attenuates ischaemic brain damage in rht rat Neuroreport,1996,7(9):1465~1468
20 Wang X、Barrone FC、Aiyar NV et al.Interleukin-I receptor and receptor amragonist gene expression after focal stroke in rats.Stroke,1999,33(1):155~161
作者单位：300111 天津市民政老年病医院, 百拇医药(林雪岩)
8 SaitoK.SuyamaK Nishida L et al.Earty increases in TNA-α,IL-6,and IL-1βlevels following transient cerebral ischemia in gerbil bran.NeuroscilLett,1996,206(20:149~152
9 Liu T、Clark R、Yong PR.Tumor necrosis faaeyor in ischemic neurons.Stroke,1994,25(7):1481~1488
10 Fassbcnder K、Rossol S、Kammer T.Proinflammmtory cytokins in serum of patients with acute cerebral ischemia; kinetics of seretion and relation to extent of brain damage and outcme of disease,JNeuurol Sci,1998,126(3):135~139
11 Tarkowski E\Roengren L\Blomstrand C、et al.Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke,2000,31(8)1393~1340
12 Dewson DA、Martion.D.Hallcnbeck JM.Inhibition of tumor necrosis factior-alpha redues focal cerebral ischemic injury in the spontaneously hypertensive rat.Neurosci lett.1996,218(10:41~44
13 Rothwell NL、Hopkis SJ.Cytokies and nercous system Ⅱ:actions and mechanisms of action Trends Neurosci，2001，2223(3):331~339
14 Merrill JE,Benveniste EN,Cytokinos in inflammatory brain lesions:helpful and harmful.TINS,1996,21(18):331~339
15 Yamade M,Hatanaka H,interieukin-6protects culture rat hippicamoral neurons againsr glutamatc-induced cell death Brain Res，1999,648(4):173
16 CampbellIL、Abrahan CR、Masliah E、et al.Neurotogic induced in reansgenjc mice by cerebral overexpression of interieukin-6.Proc Natl Sci USA,1999,96(14):10061~10065
17 YamasakiY,Masuura N Shozuhara Het al Interleykin-1 as a pathogeneti mediator of ischemic brain damage in rats.Stroke,1995,25(4):676~682
18 HaraH、Friedlander Rm、Gagliaedini Vet al Inhibition of interleukin-Ibeta coinvertion enzyme family proteases reduces ischemic and exciririxic neuronal damage.Proc Ncad Sci USA，1997,94(5):2007~2012
19 Loddick SA、Mackcnzic a.Rothwell NJ An ICE inhibitur ZVAD-DCB attenuates ischaemic brain damage in rht rat Neuroreport,1996,7(9):1465~1468
20 Wang X、Barrone FC、Aiyar NV et al.Interleukin-I receptor and receptor amragonist gene expression after focal stroke in rats.Stroke,1999,33(1):155~161
作者单位：300111 天津市民政老年病医院, 百拇医药(林雪岩)