【摘 要】目的：探讨新生儿出生缺陷发病趋势，发现其发病的高危影响因素。方法：回顾分析在我院产科出生的近两年发病例数，有效的减少新生儿出生缺陷发生率。结果：鄂州市中心医院近两年出生的4094例新生儿中有25例出生缺陷患儿，出生缺陷的病种有多指，马蹄内翻足，先天性脑积水，外耳畸形，腹裂，尿道下裂，大脑发育异常，脑静脉瘤，血管瘤，面部黑痣，腰骶部突出物，腹腔积液等。结论：新生儿出生缺陷多与基因突变、遗传因素、孕妇生活的外在环境因素有关，做好新生儿出生缺陷的三级预防工作可明显降低新生儿出生缺陷率。

    【关键词】新生儿出生缺陷；病因；监测；死亡率

    [Abstract]Objective：To explore the incidence trend of birth defects， found its pathogenesis risk factors.Methods A retrospective analysis in our hospital was born nearly two years the number of cases of， effectively reduce the incidence of birth defects in. Results The Ezhou Central Hospital in recent years 4094 newborns born in 25 cases of birth defects in children with birth defects ......