摘要：在环境水体中不断监测到医药类污染物及其活性代谢产物。控制和消减这类新的环境污染物，有效引导与管理对医药品的生产和使用，具有重要的意义。现从绿色药物化学和绿色制药技术、医药品的合理使用、医药类污染物的处理等方面对医药品生产、使用和处理过程中的有效管理原则和措施作一综述。

    关键词：医药品；生产；使用；环境保护；绿色药物化学

    中图分类号：R954 文献标识码：C文章编号：1672-979X(2007)07-0059-04

    Management of Manufacture and Application of Pharmaceutical Product from Perspective of Environmental Protection

    DU Fu-qiang1, CAO Guang-mei2, 1, FANG Yu-chen1

    (1. Shandong Bausch &Lomb Freda Phar. Co., Ltd.,Jinan 250014, China; 2. School of Pharmaceutical Science, Shandong University,Jinan 250012, China)

    Abstract：Pharmaceuticals and pharmaceutically active metabolites have been increasingly detected in field samples. In order to abate and control this emerging class of environmental pollutants, it is of great significance to effectively regulate and manage the manufacture and application of pharmaceuticals. From the aspects of pharmaceutical green chemistry and corresponding green technologies, reasonable application of pharmaceuticals, treatment of pharmaceutical contaminants and so on, this paper reviews effective principles and ways for the management, application and treatment of pharmaceutical product. ......