[摘要]目的：观察托烷司琼预防含顺铂化疗药物所致恶心、呕吐的疗效和不良反应。方法：将入选62例接受含顺铂联合化疗的恶性肿瘤患者，随机分成两组，观察组32例病人于化疗前使用托烷司琼止吐，对照组30例病人使用昂丹司琼。观察两组病人恶心、呕吐的控制情况及不良反应。结果：托烷司琼和昂丹司琼预防化疗后恶心、呕吐的有效率无明显差异(P>0.05)；但完全控制率托烷司琼优于昂丹司琼(P0.05).Tropisetron was superior to ondansetron in the complete control rate(P0.05).Conclusion:Tropisetron was safe and effective in preventing nausea and vomiting induced by chemotherapeutic drugs including cisplain.

    [Key Words]Tropisetron;Ondansetron;Chemotherapy;Nausea and vomiting

    在恶性肿瘤的临床化疗中 ......