乌贼墨对小鼠T细胞亚群和T细胞活化的影响(1)
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[摘要] 目的:研究乌贼墨对小鼠T细胞亚群和T细胞活化的影响。方法:实验组小鼠每天灌胃5%的乌贼墨0.5 ml,连续7 d。对照组小鼠给予等量生理盐水。流式细胞术检测小鼠外周血CD4+T细胞百分比、CD4+/CD8+比值及IL-2αR(CD25)表达。结果:实验组小鼠外周血CD4+T细胞百分比、CD4+/CD8+比值及IL-2αR(CD25)表达较对照组小鼠均有明显升高,而CD8+T细胞却无显著性变化。结论:乌贼墨通过增高CD4+T细胞百分比、CD4+/CD8+比值及IL-2αR(CD25)表达对小鼠免疫功能进行调节。
[关键词] 乌贼墨;免疫作用;T细胞亚群;T细胞活化
[中图分类号] R285.5 [文献标识码]A [文章编号]1673-7210(2008)07(c)-025-02
Research on the effect of the Squid Ink on T-lymphocyte subsets and the activation of T cell of KM mice
WANG Xin1,2, LI Guo-ming1,2
(1.Department of Clinical Micro-Organism Ecsomatics, Ecsomatics School, Guangdong Medical College,Dongguan 523808,China ; 2.Department of Microbiology and Immunology, Zhanjiang 524023, China)
[Abstract] Objective: To study the effects of the squid ink on T-lymphocyte subsets and the activation of the squid ink in KM mice ......
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