针刺任脉和督脉对脑缺血大鼠海马星形胶质细胞的影响(3)
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3.3 针刺任脉和督脉治疗对局灶性脑缺血星形胶质细胞的影响
本实验通过针刺任脉和督脉治疗，观察其对局灶性脑缺血大鼠的影响，从星形胶质细胞的角度来探讨针刺任脉和督脉对脑缺血后神经细胞增殖分化的机制。本实验观察到，缺血海马齿状回存在GFAP/NSE双标细胞，提示缺血后有星形胶质细胞分化为神经元，或是多能干细胞分化为星形胶质细胞。本实验结果显示，针刺任脉和督脉治疗的GFAP阳性细胞增殖幅度小于针刺督脉组，而GFAP/NSE双标细胞的增殖幅度则大于针刺督脉组，提示针刺任脉和督脉使缺血海马GFAP/NSE双标细胞增加的同时，可以调节脑缺血后缺血海马GFAP的表达，这两方面作用优于单独针刺督脉组，说明针刺任脉和督脉可抑制脑缺血后海马星形胶质细胞的过度增殖，并可促进细胞分化。任脉和督脉经穴的针刺治疗可能是脑缺血治疗的一个有前途的方法。
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(收稿日期：2008-04-08)
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