胃体癌单个转移淋巴结的临床分析
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[摘要] 目的:探讨胃体癌淋巴结单个转移的分布规律,为术中合理清除淋巴结提供理论依据。方法:回顾性分析我院收治并行手术的46例胃体癌病例的单个转移淋巴结情况,分析转移淋巴结的位置分布及其与临床病理特征间的关系。结果:46例单个转移淋巴结病例中,N1 转移35例(76.09%),N1以上11例(23.91%)。14例大弯侧癌中横向转移3例(21.43 %);32例小弯侧癌中横向转移7例(21.88%)。结论:胃体癌单个转移淋巴结规律以“邻近性”为主,其次为“横向性” 和“跳跃性”。
[关键词] 胃癌;淋巴结;临床病理特征;转移
[中图分类号] R735.2[文献标识码]A [文章编号]1673-7210(2009)02(b)-029-02
Analysis of the distribution of solitary metastastic lymph nodesin the middle of gastric cancer
JIANG Hai, WEN Shi-chun
(Department of Tumor Surgery, Benxi General Hospital of Iron or Steel Company, Benxi City, Liaoning Province, Benxi117000, China)
[Abstract] Objective: To investigate the distribution of solitary metastastic lymph nodes in the middle of gastric cancer,and lay a foundation for lymphadenectomy. Methods: 46 cases with middle gastric cancer with solitary lymph nodes were retrospectively studied. The location of metastatic lymph nodes,and the histological type were analyzed. Results: Among 46 solitary node metastases cases, 35 cases were limited to perigastric nodes(N1), while 11 cases with skipping metastasis. Among 14 cases on the greater curvature, 3 cases occured transversal metastasis. Among 32 cases on the lesser curvature, 7 cases occured transversal metastasis. Conclusion: Adjacent metastases form the primary distribution pattern of SLN in the middle of gastric carcinoma,transversal and skipping metastases being also notable.
[Key words] Gastric cancer; Lymph node; Clinical pathological characteristics; Metastasis
迄今,前哨淋巴结(sentinel lymph node,SLN)检测技术已在黑色素瘤和乳腺癌等恶性实体瘤中趋于成熟[1]。由于胃淋巴引流相对复杂,研究胃癌SLN分布规律较困难,本研究根据单个转移淋巴结就是SLN的概念[2,3],研究单个转移淋巴结、单组转移淋巴结的转移规律,以探讨胃体癌SLN分布规律,以期为进一步前瞻性检测胃癌SLN和胃癌淋巴结清除范围的正确选择提供依据。
1资料与方法
1.1一般资料
选取1999~2007年本溪市钢铁总医院肿瘤外科收治的临床资料完整的46例单个转移淋巴结胃癌的病例,所有病例术前均行胃镜检查,术后行淋巴结剪取并行病理检查。男性26例,女性20例,男女比例为1.30∶1,年龄29~78岁,平均(53±4)岁。
病例入组条件:①至少行D2手术;②术后剪取并化验淋巴结10枚以上;③病例资料完整有效。
1.2参照标准
肿瘤位置、淋巴结分组、分站、病理分级根据日本胃癌分类标准[4]。“N0.”表示淋巴结组别,“N”表示淋巴结站别。淋巴结转移至癌灶侧N1为“邻近转移”,转移至癌灶对侧N1为“横向转移”,N1以上为“跳跃转移”[5]。
1.3统计学方法
所有数据用SPSS 14.0统计学软件进行分析,单因素分析采用χ2检验,P<0.05表示差异有统计学意义。
2结果
46例单个转移淋巴结病例中,N1转移35例(76.09%),N1以上转移11例(23.91%)。其中,大弯侧癌14例,小弯侧癌32例。大弯侧癌病例转移至No.1:2例(14.29%),No.3:1例(7.14%),No.4:7例(50.00%),No.6:2例(14.29%),No.7:1例(7.14%),No.10:1例(7.14%)。小弯侧癌病例转移至No ......
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