血小板参数在小儿肺炎中的变化及临床意义(1)
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[摘要] 目的:观察不同病原引起的肺炎患儿血小板4项参数的变化。方法:回顾性研究2007年5月～2008年5月我院收治的192例细菌性、病毒性及支原体肺炎(重症肺炎78例,轻症肺炎114例)急性期和恢复期血小板数量和功能变化,并与60例对照组进行比较。血小板增多以>300×109/L为标准。结果:细菌性肺炎患儿血小板4项参数明显高于其他两组肺炎(P<0.01),急性期重症肺炎组4项参数明显高于轻症肺炎组(P<0.05),且两组恢复期均明显降低。结论:血小板数量及功能状态异常为小儿肺炎普遍存在的病理过程,更易发生于细菌性肺炎,血小板参数的变化可作为判断小儿肺炎严重程度和病情变化的一项参考指标。
[关键词] 细菌性肺炎;病毒性肺炎;支原体肺炎;血小板参数;血小板增多
[中图分类号] R563.1[文献标识码]A [文章编号]1673-7210(2009)08(a)-014-02
Clinical significance and changes of platelet parameter in child patients with pneumonia
LI Jinsong, ZHANG Li, GAO Haiying
(Department of Pediatrics, Xili People's Hospital of Nanshan District of Shenzhen City, Shenzhen 518055, China)
[Abstract] Objective: To investigate the changes and clinical significance of 4 platelet parameters in the child patients with pneumonia caused by a variety of pathogens. Methods: The medical records of 192 child patients with microbial, viral and mycoplasma pneumoniae pneumonia were retrospectively reviewed. The changes of 4 platelet parameters [platelet count (PLT); platelet hematocrit (PCT); mean platelet volume (MPV) and platelet distribution width (PDW)] in the patients with pneumonia were observed and compared with 60 normal control groups. We defined thrombocytosis as platelet count above 300×109/L. Results: The 4 platelet parameters of microbial pneumonia patients were significantly higher than those of the other two groups (P<0.01). The 4 platelet parameters of severe pneumonia group were significantly higher than those of mild pneumonia group in acute stage (P<0.05). The 4 platelet parameters of both severe pneumonia group and mild pneumonia group in convalescene stage were significantly decreased. Conclusion: The abnormality of the amount and function of platelet is the common pathological process of children pneumonia, and it is more prone to microbial pneumonia, thus the changes of platelet parameter may be reference marker for predicting the patients with pneumonia and accessing the severity ......
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