拉米夫定抗乙型肝炎病毒的临床研究
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[摘要] 目的:观察拉米夫定对慢性乙型肝炎的治疗作用。方法:随机选择70例慢性乙型肝炎患者,拉米夫定治疗组患者35例,双盲安慰剂组35例作对照,治疗时间为60周。评估包括临床症状和体征、肝功能和HBV复制指标。结果:拉米夫定组与双盲安慰剂组比较,疗效有显著性差异(P<0.05)。结论:长期服用拉米夫定治疗,可抑制HBV的复制,ALT改善明显,安全性好。
[关键词] 拉米夫定;乙型肝炎病毒;慢性乙型肝炎
[中图分类号] R51[文献标识码]A [文章编号]1673-7210(2010)01(a)-035-02
Clinical study of the antiviral effect of Lamivudine in hepatitis B
HU Ruiyue1, TIAN Bo1, TAO Xiang2
(1.The People's Hospital of Jiangxi Province, Nanchang 330000, China;2. The Children's Hospital of Jiangxi Province, Nanchang 330000, China)
[Abstract] Objective: To observe the therapeutic effect of Lamivudine for chronic hepatitis B. Methods: Among 70 cases chronic hepatitis B patients, 35 cases of patients as treatment group with the Lamivudine treatment, 35 cases of double-blind, placebo for the control group, treatment time was 60 weeks. Assessment of clinical symptoms and signs, liver function and indicators of HBV replication ......
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