非核苷类HIV-1逆转录酶抑制剂研究进展(续)

http://www.100md.com 2010年3月25日 孟 歌

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     [10]Romero DL, Olmsted RA, Poel TJ, et al. Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino) piperidine-containing bis(heteroaryl) piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors [J]. J Med Chem,1996,39(19):3769-3789.

    [11]Genin MJ, Poel TJ, Yagi Y, et al. Synthesis and bioactivity of novel bis (heteroaryl) piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs [J]. J Med Chem,1996,39(26):5267-5275 ......

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