早发冠心病急性心肌梗死患者的临床分析(1)
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[摘要] 目的:分析早发冠心病(PCAD)急性心肌梗死(AMI)患者的传统危险因素及冠状动脉的病变特点。方法:对98例PCAD-AMI患者(PCAD组)、114例晚发冠心病(LCAD)AMI患者(LCAD组)及82例非冠心病者(非冠组)的传统危险因素及冠状动脉的病变特点进行分析。结果:危险因素分析显示,PCAD组阳性家族史的比率显著高于LCAD组(P<0.01);PCAD、LCAD两组与非冠组比较,各项危险因素均偏高,差异有统计学意义(P<0.01或P<0.05)。冠状动脉造影结果显示,PCAD组单支病变比率比LCAD组高(P<0.01)。PCAD组的单支闭塞率与LCAD组相近,未见双支闭塞者。PCAD组的每例单个支架置入比率显著高于LCAD组(P<0.01)。结论:PCAD-AMI患者的发病与传统危险因素密切相关;PCAD组的冠状动脉病变轻于LCAD组;经皮冠脉介入术是PCAD-AMI患者十分有效的治疗方法之一。
[关键词] 早发冠心病;急性心肌梗死;冠状动脉病变;危险因素
[中图分类号] R541.4[文献标识码]A [文章编号]1673-7210(2010)05(c)-015-03
Clinical analysis of premature coronary artery disease in patients with acute myocardial infarction
ZHANG Xiangqun
(Department of Cardiology, Linzi People's Hospital of Zibo City, Zibo 255400, China)
[Abstract] Objective: To analyze the traditional risk factors and coronary lesion characteristics of patients with premature coronary artery disease (PCAD) with acute myocardial infarction (AMI). Methods: The traditional risk factors and coronary lesion characteristics of angiography and interventional treatment of 98 PCAD-AMI patients (PCAD group), 114 late-onset coronary artery disease (LCAD) AMI patients (LCAD group) and 82 non-coronary artery disease patients (non-CAD group) were analyzed. Results: Risk factor analysis showed that the ratio of positive family history of PCAD group was significantly higher than that of LCAD group (P<0.01); the risk factors of PCAD group and LCAD group were higher than those of non-CAD group (P<0.01 or P<0.05). Coronary angiography result showed that the incidence of single-vessel disease in PCAD group was higher than that in LCAD group (P<0.01). The single vessel occlusion rate of PCAD group was similar to that of LCAD group and there was no double-vessel occlusion. The single stent per patient ratio of PCAD group was significantly higher than that of LCAD group (P<0.01). Conclusion: PCAD-AMI is closely related to the traditional risk factors. The coronary lesions of PCAD group are lighter than those of LCAD group. Percutaneous coronary intervention is a very effective treatment for patients with PCAD-AMI.
[Key words] Premature coronary artery disease; Acute myocardial infarction; Coronary lesion; Risk factor ......
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