351例泌尿生殖道支原体感染情况及耐药分析(1)
 |
| 第1页 |
参见附件(1373KB，2页)。
[摘要] 目的:了解泌尿生殖道支原体的感染情况及耐药现状,为合理用药提供可靠依据。方法:采用珠海益民生物工程制品厂生产的支原体培养、鉴定、药敏一体试剂盒,进行支原体培养、鉴定,同时对14种抗生素进行耐药性检测。结果:2009年7～12月年检测标本351份,阳性143份,阳性率为44.1%。351例非淋菌性尿道炎(NGU)患者中,支原体感染阳性192例(39.67%),其中解脲脲支原体(Uu)感染155例(32.02%);人支原体(Mh)感染11例(2.27%);Uu+Mh混合感染26例(5.37%)。对支原体敏感的前5位药物依次为交沙霉素、克拉霉素、罗红霉素、强力霉素、四环霉素。结论:NGU患者主要以Uu感染为主,交沙霉素、克拉霉素可以作为本地区NGU患者治疗的首选药物。
[关键词] 泌尿生殖道;支原体感染;耐药性
[中图分类号] R375[文献标识码] A [文章编号] 1673-7210(2010)06(a)-172-02
Infection and drug resistance on 351 cases of mycoplasma infection
PAN Rixing, SU Fanghua, LI Yacai
(Department of Pharmacy, the Third Affiliated Hospital of Guangdong Medical University, Maoming 525011, China)
[Abstract] Objective: In order to provide a reliable by understanding of mycoplasma infection and drug resistance status. Methods: We used bio-engineering products made in Zhuhai Yimin company, included of plant mycoplasma culture, identification and antimicrobial susceptibility body kit. For mycoplasma culture, identification, and 14 kinds of antibiotics resistance were tested. Results: 351 sample were test from July 2009 to December 2009, 143 were positive, the positive rate was 44.1%. The results of 351 cases of NGU patients positive for mycoplasma infection in the number of 192 cases (39.67%) in which the number of Uu infection in 155 cases (32.02%); Mh infection in the number of 11 cases (2.27%); Uu+Mh number of mixed infection was 26 cases (5.37%). The first four pairs of Mycoplasma-sensitive substances, in order josamycin, clarithromycin, roxithromycin, doxycycline, tetracycline. Conclusion: Uu infection mainly in patients with NGU mainly josamycin, clarithromycin and NGU in this region can be used for drug of first choice in patients.
[Key words] Genitourinary tract; Mycoplasma infection; Drug resistance
支原体是一类无细胞壁,大小介于细菌和病毒之间的原核细胞型微生物,通常寄生在泌尿生殖道黏膜的表面,是引起非淋菌性尿道炎(NGU)的重要病原菌之一,也与宫颈炎、输卵管炎、前列腺炎及不孕不育等关系密切[1]。随着各种抗生素的不规范使用,使得支原体的耐药性也不断发生变化,多重耐药明显增加,并根据药敏合理地选用抗菌药物,以抑制耐药菌株的产生十分重要。笔者对2009 年7～12月我院妇产科、泌尿外科、性病科的351 份标本的支原体培养及药敏情况进行统计分析,现报道如下:
1 资料与方法
1.1 一般资料
2009 年7～12月,在我院妇产科、泌尿外科、皮肤科就诊,疑为非淋菌性尿道(宫颈)炎者,其中男26例,年龄18～56岁;女324例,年龄20～54岁。男性患者大多有尿道刺痒、刺痛或烧灼感,少数有小腹坠胀;女性患者大多有白带增多,外阴部瘙痒等不适 ......
您现在查看是摘要介绍页，详见PDF附件(1373KB，2页)。