无创机械通气治疗急性呼吸窘迫综合征临床分析(1)
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[摘要] 目的：探讨无创机械通气治疗急性呼吸窘迫综合征的临床疗效。方法：选取2007年1月~2010年1月进入我院监护室的急性呼吸窘迫综合征患者96例，在综合治疗的基础上，对其进行无创机械通气治疗，观察患者治疗前与治疗后的呼吸频率、心率、血压、pH、SaO2、PaO2、PaCO3、氧合指数(PaO2/FiO2)等指标。结果：96例急性呼吸窘迫综合征患者经过无创机械通气治疗后，原有呼吸困难症状明显改善，pH、SaO2、PaO2、PaO2/FiO2等指标上升明显，与治疗前相比差异有统计学意义(P<0.05)；呼吸频率、心率、血压、PaCO3等指标明显下降，与治疗前相比差异有统计学意义(P<0.05)。结论：无创机械通气治疗能够迅速缓解急性呼吸窘迫综合征患者的临床症状，并改善患者的各项血气指标，值得在临床中推广应用。
[关键词] 无创机械通气；急性呼吸窘迫综合征；临床分析
[中图分类号] R563[文献标识码]A [文章编号]1673-7210(2010)11(a)-046-02
Clinical analysis of non-invasive mechanical ventilation for acute respiratory distress syndrome
ZHANG Yunheng, LI Hui, DU Zhengchi
(The Eighth People's Hospital of Qingdao City, Qingdao 266100, China)
[Abstract] Objective: To investigate the efficacy of the non-invasive mechanical ventilation in acute respiratory distress syndrome. Methods: 96 patients with acute respiratory distress syndrome from January 2007 to January 2010 in our hospital were selected, they were used non-invasive mechanical ventilation on the basis of the combined treatment. Before and after treatment respiratory rate, heart rate, blood pressure, pH, SaO2, PaO2, PaCO3, oxygenation index (PaO2/FiO2) were measured. Results: After treatment of 96 cases with acute respiratory distress syndrome, the original difficulty breathing symptoms improved, pH, SaO2, PaO2, PaO2/FiO2 increased significantly, there was a significant difference compared with before treatment (P<0.05); respiratory rate, heart rate, blood pressure, PaCO3 decreased significantly compared with before treatment (P<0.05). Conclusion: Non-invasive mechanical ventilation in acute respiratory distress syndrome can quickly relieve the clinical symptoms and improve the blood gas analysis in patients, it is worthy of clinical use.
[Key words] Non-invasive mechanical ventilation; Acute respiratory distress syndrome; Clinical analysis
急性呼吸窘迫综合征(ARDS)是发生于休克、创伤、严重感染、误吸及急性重症胰腺炎等疾病过程中出现肺泡-毛细血管膜损伤导致的以进行性低氧血症、呼吸窘迫为特征的临床综合征[1]。机械通气是治疗急性呼吸窘迫综合征非常有效的方法，机械通气又分为有创性机械通气和无创性机械通气，由于有创机械通气方法有创伤性、并发症多，最突出的问题是带有气管内导管，易于引起下呼吸道感染和呼吸机相关肺炎，因此无创性机械通气在临床中的应用日益广泛。本文调查了我院2007年1月～2010年1月无创性机械通气在96例急性呼吸窘迫症患者中的使用情况 ......
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