代谢组学在中药制剂体内评价的研究进展(1)
[摘要]目的:总结代谢组学在中药制剂体内评价中的研究现状。 方法:收集近几年国内外的相关文献,对代谢组学在中药制剂体内评价的最新研究情况进行分析归纳。 结果:代谢组学在中药制剂体内评价中得到了广泛应用,包括中药整体药效评价、物质基础的研究、毒理学、药动学研究等。 结论:代谢组学是中药制剂体内评价的一个重要途径和手段, 具有广泛的应用价值。[关键词] 代谢组学;中药制剂;体内评价;药效学;毒理学
[中图分类号] R28[文献标识码]A [文章编号]1673-7210(2010)11(b)-006-03
Research on metabonomics in vivo evaluation of Traditional Chinese Medicine preparations
CUI Yifei, HUANG Shengwu, YAN Lu
(Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China)
[Abstract] Objective: To summarize the research on metabonomics in vivo evaluation of Traditional Chinese Medicine preparations. Methods: Summarized the latest study on metabonomics in vivo evaluation of Traditional Chinese Medicine preparation by collecting of articles at home and abroad in recent years. Results: Metabonomics were widely used in vivo evaluation of Traditional Chinese Medicine preparations, including the overall efficacy evaluation, material-based research, toxicology, pharmacokinetics. Conclusion: Metabonomics, as a significant ways and means in vivo evaluation in Traditional Chinese Medicine preparation, is of extensive applicable value. ......
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