[摘要] 目的：探讨2型糖尿病胰岛素抵抗与血清IL-6、TNF-α、hs-CRP及FFA水平的相关性。方法：选取2008年12月~2010年9月在我院进行治疗的50例2型糖尿病患者为观察组，同时选取50名健康体检人员为对照组，对两组人员的血清IL-6、TNF-α、hs-CRP及FFA水平与胰岛素抵抗指数(HOMA-IR)进行统计及比较。结果：经研究比较发现，观察组的血清IL-6、TNF-α、hs-CRP及FFA水平与HOMA-IR均高于对照组，两组结果数据比较差异有统计学意义(P<0.05或P<0.01)。结论：2型糖尿病胰岛素抵抗与血清IL-6、TNF-α、hs-CRP及FFA水平有极大的相关性，值得进一步研究及探讨。

    [关键词] 2型糖尿病 胰岛素抵抗 IL-6 TNF-α hs-CRP FFA 相关性

    [中图分类号] R587[文献标识码]B[文章编号]1673-7210(2011)02(b)-159-02

    Study on the correlation between insulin resistance and various serum factors in type 2 diabetes mellitus

    MENG Yansheng, ZHANG Bing, ZHAO Yingmei, MENG De

    (The Second People's Hospital of Pingnan City, Guangxi Zhuang Autonomous Region, Pingnan 537307, China)

    [Abstract] Objective：To study the correlation between insulin resistance and serum IL-6,TNF-α, hs-CRPand FFA in type 2 diabetes mellitus. Methods: 50 patients with type 2 diabetes mellitus in our hospital from December 2008 to September 2010 were selected as observation group ......