银杏达莫治疗急性重度有机磷农药中毒合并心肌损害的临床观察(1)
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[摘要] 目的：探讨银杏达莫在治疗急性重度有机磷农药中毒合并心肌损害的临床效果。方法：将2007年1月～2010年9月来我院治疗的60例急性重度有机磷农药中毒患者随机分为观察组和对照组，每组30例，其中观察组行银杏达莫和常规解毒治疗，对照组给予FDP(1，6二磷酸果糖)对心肌进行保护加常规解毒方式治疗，观察两组的临床治疗效果。结果：两组治疗前各指标比较差异无统计学意义(P>0.05)；治疗后两组心肌酶谱均较住院之初显著下降，但观察组各项指标的下降幅度更明显(P<0.05)；两组住院时间、CHE(胆碱酯酶)达正常时间和阿托品用量比较，差异有统计学意义(P<0.05)。结论：在治疗急性重度有机磷农药中毒合并心肌损害方面，银杏达莫具有明显的疗效，可大大提高治愈率，有效缩短住院时间。
[关键词] 银杏达莫；有机磷农药中毒；心肌损害
[中图分类号] R139+.3 [文献标识码] A [文章编号] 1673-7210(2011)06(c)-094-02
Clinical observation of acute severe organophosphorus pesticide poisoning with myocardial injury treat with Yinxingdamo
ZHAO Mingyou, YANG Rongqiang, DAI Jinzhong
Department of Emergency, People's Hospital of Xiangxi Autonomous Prefecture, Hu′nan Province, Xiangxi 416000, China
[Abstract] Objective: To investigate the clinical effect of acute severe organophosphorus pesticide poisoning with myocardial injury treated with Yinxingdamo. Methods: 60 patients of acute severe organophosphorus pesticide poisoning from January 2007 to September 2010 in our hospital were randomly divided into observation group and control group, 30 cases each group, patients in observation group were treated with Yinxingdamo and the conventional antidotes, patients in control group were treated with FDP (1, 6-diphosphofructose) to protect cardiac muscle and the conventional antidotes, to observe clinical effect of two groups. Results: The difference of each index in two groups before treatment was no statistically significant (P>0.05). After treatment, myocardial enzyme of two groups all decreased, but the observation group index declines more obvious (P<0.05). the difference of hospitalization time, CHE of normal time and atropine dosage between groups had statistical significance (P<0.05). Conclusion: In treatmet of acute severe organophosphorus pesticide poisoning with myocardial injury, Yinxingdamo has obvious effects, it can significantly improve the cure rate, shorten hospital stay. ......
[摘要] 目的：探讨银杏达莫在治疗急性重度有机磷农药中毒合并心肌损害的临床效果。方法：将2007年1月～2010年9月来我院治疗的60例急性重度有机磷农药中毒患者随机分为观察组和对照组，每组30例，其中观察组行银杏达莫和常规解毒治疗，对照组给予FDP(1，6二磷酸果糖)对心肌进行保护加常规解毒方式治疗，观察两组的临床治疗效果。结果：两组治疗前各指标比较差异无统计学意义(P>0.05)；治疗后两组心肌酶谱均较住院之初显著下降，但观察组各项指标的下降幅度更明显(P<0.05)；两组住院时间、CHE(胆碱酯酶)达正常时间和阿托品用量比较，差异有统计学意义(P<0.05)。结论：在治疗急性重度有机磷农药中毒合并心肌损害方面，银杏达莫具有明显的疗效，可大大提高治愈率，有效缩短住院时间。
[关键词] 银杏达莫；有机磷农药中毒；心肌损害
[中图分类号] R139+.3 [文献标识码] A [文章编号] 1673-7210(2011)06(c)-094-02
Clinical observation of acute severe organophosphorus pesticide poisoning with myocardial injury treat with Yinxingdamo
ZHAO Mingyou, YANG Rongqiang, DAI Jinzhong
Department of Emergency, People's Hospital of Xiangxi Autonomous Prefecture, Hu′nan Province, Xiangxi 416000, China
[Abstract] Objective: To investigate the clinical effect of acute severe organophosphorus pesticide poisoning with myocardial injury treated with Yinxingdamo. Methods: 60 patients of acute severe organophosphorus pesticide poisoning from January 2007 to September 2010 in our hospital were randomly divided into observation group and control group, 30 cases each group, patients in observation group were treated with Yinxingdamo and the conventional antidotes, patients in control group were treated with FDP (1, 6-diphosphofructose) to protect cardiac muscle and the conventional antidotes, to observe clinical effect of two groups. Results: The difference of each index in two groups before treatment was no statistically significant (P>0.05). After treatment, myocardial enzyme of two groups all decreased, but the observation group index declines more obvious (P<0.05). the difference of hospitalization time, CHE of normal time and atropine dosage between groups had statistical significance (P<0.05). Conclusion: In treatmet of acute severe organophosphorus pesticide poisoning with myocardial injury, Yinxingdamo has obvious effects, it can significantly improve the cure rate, shorten hospital stay. ......
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