[摘要] 目的：分析不孕不育夫妇生殖道支原体感染状况及耐药情况，为生殖保健提供参考。方法：对288对不孕不育夫妇(观察组)和51对已生育的健康夫妇(对照组)进行生殖道支原体培养及药敏试验，观察支原体感染率、感染支原体种类及耐药情况差异。结果：观察组支原体阳性率为73.3%，对照组支原体阳性率为36.3%，观察组高于对照组，差异有高度统计学意义(P<0.01)。药敏结果显示，克拉霉素、强力霉素敏感率高(89.3%、88.2%)，红霉素、洛美沙星的耐药率高(81.5%、91.1%)。结论：生殖道支原体感染与不孕不育有着密切的相关性，且支原体对常用抗生素的耐药性较高。

    [关键词] 不孕不育；支原体感染；耐药性

    [中图分类号] R711.6 [文献标识码] B [文章编号] 1673-7210(2011)07(a)-156-02

    Analysis of urogenital mycoplasma infection and resistance to antibiotics on infertile patients

    LONG Feng

    Maternal and Child Care Service Centre of Shenzhen City affiliated to Nanfang Medical University, Guangdong Province,Shenzhen 518028, China

    [Abstract] Objective: To investigate urogenital mycoplasma infection in infertile patients and the resistance to antibiotics. Methods: All specimens from 288 sterile couples (observation group) and 51 healthy couples (control group) were cultured for mycoplasma, then the drug susceptive test was done. The infection rate, type of mycoplasma and drug resistance rate were contrasting. Results: The positive rate of mycoplasma infection in observation group (73.3%) was higher than control group(36.3%), there were significant differences between the two groups. The susceptive test result showed that the susceptive rate of clarithromycin and doxycycline (89.3%, 88.2%) was higher, drug resistance rate of erythromycin and lomefloxacin was higher(81.5%, 91.1%). Conclusion: The infection of urogenital mycoplasma is correlative with infertility, and mycoplasma shows different resistance to commonly used antibiotics. ......