高血压与中年人记忆功能障碍的关系(1)
 |
| 第1页 |
参见附件(2065KB，2页)。
[作者简介] 崔永生(1962-)，男，河南开封人，河南大学硕士生导师，从事心血管临床研究。
[摘要] 目的：探讨高血压对中年人记忆功能的影响。方法：采用临床记忆量表对200例原发性高血压患者(病例组)和100例健康体检者(对照组)进行记忆功能测定。结果：病例组记忆商(memory quotient，MQ)得分(81.45±12.70)分，对照组MQ得分(91.60±10.28)分，两组MQ得分比较差异有高度统计学意义(P<0.01)；病例组中血压正常组指向记忆得分(13.69±4.69)分，联想学习得分(15.43±3.39)分，高血压组两项得分分别为(12.25±5.38)分和(14.14±4.73)分，差异有统计学意义(P<0.05)。结论：高血压可损害中年人的记忆功能，将血压控制正常水平可减轻这种损害。
[关键词] 中年；高血压；记忆功能
[中图分类号] R544.1[文献标识码]B [文章编号]1673-7210(2011)07(c)-124-02
Relationship between hypertension and memory dysfunction in middle-aged people
CUI Yongsheng1,2, SHEN Minghui1,2, YU Ronghuan1, TIAN Yanping1
1.The First People's Hospital of Kaifeng City, He'nan Province, Kaifeng 475000, China; 2.Clinical Medical Key Laboratory, the First People's Hospital of Kaifeng City, He'nan Province, Kaifeng 475000, China
[Abstract] Objective: To explore the impact of hypertension on memory in middle-aged people. Methods: Clinical memory scale was used to measure the memory of 200 cases of essential hypertension patients (case group) and 100 cases of health-examined individuals (control group). Results: The MQ scores of the case group were (81.45±12.70) scores, while the control group were (91.60±10.28) scores, the difference was significant (P<0.01); The scores of the directive memory and the associative learning of the normal blood pressure individuals were (13.69±4.69) scores and (15.43±3.39) scores, while the high blood pressure individuals were (12.25±5.38) scores and (14.14±4.73) scores, the difference was significant (P<0.01). Conclusion: Hypertension can damage the memory function in middle-aged people, which can be reduced when the blood pressure is controlled at the normal level.
[Key words] Middle-age; Hypertension; Memory function
既往研究表明，心血管病危险因素如高血压等可影响认知功能，无脑卒中的高血压患者有记忆和认知功能的减退[1-4]。但这些研究年龄范围不同，且多以老年人为研究对象，高血压患者在中年时期是否已经存在记忆功能障碍尚未见报道。本研究选择45~60岁的中年高血压患者和健康对照者进行记忆功能测定，旨在探讨高血压对中年人记忆功能的影响。
1 资料与方法
1.1 一般资料
本次共调查300例研究对象。病例组为2008年3月~2010年10月在我院高血压科、心内科和神经内科已确诊的原发性高血压病患者200例，其中，男111例，女89例，平均(53.81±5.07)岁；对照组为在本院体检中心体检的健康者100例，其中，男50例，女50例，平均(54.12±4.90)岁。根据血压是否控制在正常水平将病例组分为血压正常组(94例)和高血压组(106例)两个亚组：血压正常组中，男51例，女43例；高血压组中，男60例，女46例。病例组和对照组在性别、年龄、文化程度、受教育年限、Zung分值、空腹血糖、血脂上比较，差异均无统计学意义(P>0 ......
您现在查看是摘要介绍页，详见PDF附件(2065KB，2页)。