卡托普利注射液配合降压沟放血治疗高血压急症的临床疗效(1)
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[作者简介] 袁小兰(1967-)，女，学士学位，主治医师，主要从事心血管疾病的研究。刘宇宏(1968-)，男，博士，副主任医师，主要从事心血管疾病的研究。
[摘要] 目的：探讨卡托普利注射液配合降压沟放血治疗高血压急症的疗效和安全性。方法：对68例高血压急症患者给予卡托普利注射液25 mg加入5%葡萄糖注射液20 ml静注，同时一侧降压沟刺络放血，治疗后5、10、15、30 min，1、2、4 h观察血压、心率、临床表现和不良反应。结果：治疗后5 min收缩压和舒张压开始下降，15～30 min血压下降较明显(P<0.01)，头痛、视物模糊、呼吸困难等症状明显减轻，1 h血压降低约25%，之后血压维持在安全范围，总有效率为97.1%。结论：卡托普利注射液配合降压沟放血降压速度快，降压作用平稳，能迅速改善临床症状，未见不良反应发生，符合高血压急症的治疗原则；对伴有心力衰竭的高血压急症患者具有明显改善心功能的作用，且无须严格控制滴速，操作简单，安全有效，值得基层医疗单位推广应用。
[关键词] 卡托普利注射液；降压沟放血疗法；高血压急症；疗效
[中图分类号] R972.4[文献标识码]B[文章编号]1673-7210(2011)07(c)-149-03
The clinical effect of Captopril Injection combined with Jinagyagou of bloodletting in the treatment of hypertensive emergencies
YUAN Xiaolan1, LIU Yuhong2
1.Health Service Station of Community Moshan, Huazhong University of Science and Technology, Guanshan Road, Hongshan District of Wuhan City, Hubei Province, Wuhan 430074, China; 2.Department of Cardiology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Hubei Province, Wuhan 430022, China
[Abstract] Objective: To evaluate the efficacy and safety of Captopril Injection combined with Jinagyagou of bloodletting in treatment of hypertensive emergency. Methods: 25 mg Captopril Injection which was dissolved in 20 ml 5% Glucose was injected intra vena of 68 patients with hypertensive emergency, and these patients were treated by bloodletting puncture in Jiangyagou at the same time. After that, blood pressure, heart rate, clinical manifestations and adverse reactions were measured at 5, 10, 15, 30 minutes and 1, 2, 4 hours. Results: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) decreased at 5 minutes after these patients were treated. BP decreased significantly at 15 to 30 minutes, clinical manifestations such as headache, sight blur, difficulty in breathing could be alleviated obviously, the blood pressure was reduced about 25% within an hour and BP was maintained at safe range during the next 2 to 4 hours ......
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