QTc间期离散度与2型糖尿病及其合并冠心病的关系(1)
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[摘要] 目的：研究2型糖尿病及其合并冠心病QTc间期离散度(QTcd)的变化。方法：测量计算86例2型糖尿病患者的QTcd，并分为糖尿病1组(未合并冠心病)44例，糖尿病2组(合并冠心病)42例，并测量40例冠心病患者(冠心病组)的QTcd及40例对照组的QTcd，进行组间对比。结果：糖尿病1组的QTcd较对照组显著增大(P<0.01)，糖尿病2组的QTcd较糖尿病1组增大，差异有统计学意义(P<0.05)，糖尿病1组及冠心病组的QTcd均较对照组增大(P<0.01)，虽然糖尿病1组的QTcd较冠心病组略小，但该两组间差异无统计学意义(P>0.05)，糖尿病2组与冠心病组比较，QTcd显著增大，差异有统计学意义(P<0.05)。结论：测量QTcd对预测2型糖尿病心血管事件有重要意义。
[关键词] 2型糖尿病；QTc间期离散度；冠心病
[中图分类号] R541.4[文献标识码]B[文章编号]1673-7210(2011)07(c)-158-02
The relationship between QTc interval dispersion and type 2 diabetes mellitus and its with coronary heart disease
ZHANG Jianying, LI Fengju, ZHANG Yuhang
Department of Cadre, Beijing Electric Power Hospital, Beijing 100073, China
[Abstract] Objectives: To study QTc dispersion (QTcd) in patients with type 2 diabetes mellitus and in those combined with both type 2 diabetes mellitus and coronary heart disease (CHD). Methods: 86 patients with type 2 diabetes mellitus were divided into 2 groups, diabetes group 1 of 44 patients (without CHD), diabetes group 2 of 42 patients (with CHD), at the same time, measured QTcd in 40 patients only with coronary heart disease (CHD) and that in control group of 40 cases, comparedthem with each other. Results: QTcd in diabetes group 1 was larger than that in control group (P<0.01), QTcd in diabetes group 2 was larger than that in diabetes group 1, there was significant difference between them (P<0.05). QTcd in diabetes group 1 and group CHD were all larger than that in control group (P<0.01), though QTcd in diabetes group 1 waslittle shorter than that in group CHD, but there was no significant difference between them (P>0.05). QTcd in diabetes group 2 was larger than that in group CHD, there was significant difference between them (P<0.05). Conclusion: It is very useful of predicting the incident of cardiovascular disease in type 2 diabetes mellitus to measure QTcd.
[Key words] Type 2 diabetes mellitus; QTcd; Coronary heart disease
QTc离散度(QTc dispersion ......
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