妊娠高血压综合征视网膜病变临床分析(1)
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[摘要] 目的：观察分析妊娠高血压综合征(PIH)视网膜病变与PIH病情程度的关系。方法：选取PIH孕产妇280例，观察其视网膜情况、血压、蛋白尿、血细胞比容。结果：280例PIH孕产妇中，共计215例出现了不同程度的视网膜病变，发生率为76.8%，其中妊娠高血压、子痫前期轻度、子痫前期重度、子痫视网膜病变发生率分别为59.5%、76.2%、97.7%、100.0%。在平均动脉压<140 mm Hg(1 mm Hg=0.133 kPa)和≥140 mm Hg的病例中，视网膜病变发生率分别为70.6%、92.4%；尿蛋白≤++者和≥+++者，视网膜病变发生率分别为70.6%、89.2%；血细胞比容≤0.35者和>0.35者，视网膜病变发生率分别为69.6%、84.8%，差异均具有统计学意义(P<0.01)。此外，不同视网膜病变分期之间差异具有统计学意义(P<0.01)。结论：随着PIH病情加重，视网膜病变发生率增加，并且随着PIH病情加重，视网膜病变程度加重。通过观察视网膜情况可以在一定程度上评估PIH病情严重程度。
[关键词] 妊娠高血压综合征；视网膜病变；高危妊娠；妊娠并发症
[中图分类号] R714.24+6[文献标识码]A [文章编号]1673-7210(2011)07(c)-165-02
The clinic analysis of retinopathy in pregnancy induced hypertension
CHENG Guangjie, ZHOU Hao
Department of Obstetrics and Gynecology, Maternity Hospital of Changchun, Jilin Province, Changchun 130042, China
[Abstract] Objective: To observe and analyze the relationship between retinopathy in pregnancy induced hypertension (PIH) and severity of PIH. Methods: Two hundred and eighty women were involved in this study, whose retina, blood pressure, albuminuria, volume of packed red blood cells (VPRBC) was observed. Results: Various retinopathy appeared in 215/280 cases (76.8%). The incidence of retinopathy was 59.5%, 76.2%, 97.7% and 100.0% respectively in stage of hypertension, mild eclampsism, severe eclampsism and eclampsia. And the rate was 70.6% and 92.4% respectively in cases of mean arterial pressure <140 mm Hg(1 mm Hg=0.133 kPa) and ≥140 mm Hg. While it was 70.6% and 89.2% respectively in cases of albuminuria≤++ and ≥+++; 69.6% and 84.8% in cases of VPRBC≤0.35 and >0.35. The differences between those were statistically significant (P<0.01). Additionally, the differences in stages of retinopathy were statistically significant (P<0.01). Conclusion: The incidence of retinopathy increases with PIH exacerbations. And the more serious with the PIH, the more aggravated retinopathy. Severity of PIH may be evaluated in some degree by retinopathy.
[Key words] Pregnancy induced hypertension; Retinopathy; High risk pregnancy; Pregnancy complication ......
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