H型高血压与急性心肌梗死的相关性分析(1)
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[摘要] 目的：探讨H型高血压与急性心肌梗死(AMI)的相关性。方法：选取我院2009年6月~2010年12月收治的120例高血压合并冠心病的患者为研究对象，其中按照高血压同型半胱氨酸(Hcy)水平的不同，将其分为H型高血压组(Hcy≥10 μmol/L)59例和单纯性高血压组(Hcy<10 μmol/L)61例，比较H型高血压组中AMI患者及非AMI患者的Hcy、三酰甘油(TG)、胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)，并比较单纯性高血压组的AMI患者及非AMI患者的以上指标。结果：H型高血压组AMI患者的比例显著高于单纯性高血压组(P<0.05)。H型高血压组中，AMI患者的Hcy水平显著高于非AMI患者(P<0.05)，其他指标差异无统计学意义(P>0.05)。单纯性高血压组中，AMI患者的Hcy水平显著低于非AMI患者，TC、LDL-C显著高于非AMI患者(P<0.05)，其他指标差异无统计学意义(P>0.05)。经多元性回归分析发现，H型高血压是AMI的一个独立影响因素。结论：H型高血压与AMI密切相关，能降低Hcy水平，可有效降低心血管事件的发生率。
[关键词] H型高血压；急性心肌梗死；同型半胱氨酸
[中图分类号] R542.22 [文献标识码] B [文章编号] 1673-7210(2011)11(a)-186-03
Correlation analysis of H-hypertension and acute myocardial infarction
WU Meifang
Department of Cardiology, Geriatric Hospital, Hu'nan Province, Changsha 410016, China
[Abstract] Objective: To investigate the correlation between H-hypertension and acute myocardial infarction (AMI). Methods: 120 patients with hypertension combined with coronary heart diseases admitted and treated in our hospital from June 2009 to December 2010 were selected. According to different levels of hypertension homocysteine (Hcy), they were divided into the H-hypertension group (Hcy≥10 μmol/L) with 59 patients and the simple hypertension group (Hcy<10 μmol/L) with 61 patients. Hcy, triglyceride (TG), cholesterol (TC), low density lipoprotein (LDL-C) and high density lipoprotein (HDL-C) of patients with AMI and patients without AMI in the H-hypertension group were compared. These above indicators of patients with AMI and patients without AMI in the simple hypertension group were also compared. Results: The proportion of patients with AMI in the H-hypertension group was significantly higher than that of the simple hypertension group (P<0.05). In the H-hypertension group, the Hcy level of the patients with AMI was significantly higher than that of those without AMI (P<0.05), and the other indicators had no significant differences (P>0.05). In the simple hypertension group, the Hcy level of the patients with AMI was significantly lower than that of those without AMI while TC and LDL-C were significantly higher (P<0 ......
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