脑出血患者血清胆固醇的表达(1)
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[摘要] 目的：探讨血清胆固醇(TC)对脑出血的影响。方法：选取我院2007年8月~2010年9月收治的40例脑出血患者作为观察组，选取40例健康人为对照组，比较两组人群胆固醇水平，并观察胆固醇含量对脑出血部位和患者预后的影响。结果：本研究表明观察组患者TC、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平均低于对照组，两组比较差异有统计学意义(P<0.05)；穿通支动脉出血组胆固醇、三酰甘油(TG)含量明显高于皮层动脉出血组，两组比较差异有统计学意义(P<0.05)；胆固醇含量与恶性血管事件发生率呈正相关。结论：脑出血急性期LDL-C水平明显下降，但是尚不能代表出血前的血脂水平，TG升高可能是脑梗死的重要因素，胆固醇含量与脑出血患者恶性血管事件的发生率在一定范围内呈正相关。
[关键词] 血清胆固醇；急性脑出血；恶性心血管事件；预后
[中图分类号] R743.34 [文献标识码] A [文章编号] 1673-7210(2011)11(b)-041-02
Serum cholesterol expression in cerebral hemorrhage patients
YU Li
Department of Neurology, the Central Hospital of Yiyang City, Hu′nan Province, Yiyang 413000, China
[Abstract] Objective: To investigate the influence of serum cholesterol (TC) on cerebral hemorrhage. Methods: The clinical data of 40 cases with cerebral hemorrhage in our hospital from August 2007 to September 2010 were selected as the observation group, 40 healthy people were selected as control group. The cholesterol levels of the two groups were compared, the influence of cholesterol levels on the cerebral hemorrhage parts and prognosis of patients were observed. Results: TC, LDL-C, HDL-C levels of the observation group were significantly lower than those of the control group, and there was a significantly difference between the two groups (P<0.05); TC, TG level of the artery in after the cerebral hemorrhage groupwas significantly higher than those of cortex arterial hemorrhage group (P<0.05); there was a positive correlation between the cholesterol content and m alignant vascular events incidence. Conclusion: TC, LDL-C in cerebral hemorrhage in the acute phase decline obviously, but they are not representative of blood lipid level before bleeding. TG hypertension may be an important factor in a cerebral infarction and cerebral hemorrhage, cholesterol content in patients with m alignant vascular events in the incidence of certain scope are positively correlated.
[Key words] Serum cholesterol; Acute cerebral hemorrhage; Adverse cardiovascular events; Prognosis
我国脑出血患者约占脑血管疾病患者总数的10%，是脑血管疾病中死亡率最高的疾病，因此预防脑出血并找到脑出血的危险因素十分必要[1]。有资料报道脑出血的发生与血清胆固醇水平呈负相关，本文通过回顾我院40例脑出血患者的临床资料，分析血清胆固醇水平对脑出血的影响，现报道如下：
1 资料与方法
1.1 一般资料
选取我院2007年8月~2010年9月收治的40例脑出血患者作为观察组，选取40例健康人作为对照组。观察组中，男27例，女13例；年龄55~79岁，平均(65.5±6.7)岁；穿通支动脉出血21例，皮层动脉出血19例。对照组中，男26例，女14例；年龄56~80岁，平均(66.5±7.9)岁。两组患者在年龄、性别等方面比较差异无统计学意义(P>0.05)，具有可比性。
1.2方法
患者入院后详细了解病史，全面体格检查并进行记录，禁食12 h，第2日清晨抽取空腹静脉血，仪器采用岛津CL8000全自动生化分析仪做血脂测定，包括胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)等 ......
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