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编号:12144480
步长脑心通胶囊对冠心病合并高血脂患者的临床疗效(1)
http://www.100md.com 2011年12月5日 吴结红
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     [摘要] 目的:探讨步长脑心通对冠心病合并高血脂患者的临床疗效。方法:将我院2008年1月~2011年4月收治的100例冠心病合并高脂血症患者随机分成两组,对照组50例使用常规治疗治疗,观察组50例在对照组治疗的基础上加用步长脑心通胶囊,以1个月为1个疗程,对比两组治疗前后三酰甘油(TG)、总胆固醇(CHOL)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白-A1(Apo-A1)、载脂蛋白-B(Apo-B)的水平变化。结果:1个疗程后,观察组与对照组的TG[(1.74±0.45)mmol/L vs(2.33±1.02)mmol/L]、CHOL[(6.34±0.58)mmol/L vs(7.57±2.37)mmol/L]、LDL-C[(2.36±0.32)mmol/L vs(2.99±0.79)mmol/L]、Apo-A1[(1.35±0.67)mmol/L vs(1.59±0.78)mmol/L]、Apo-B[(1.57±0.37)mmol/L vs(3.08±1.09)mmol/L]比较,观察组均低于对照组,差异均有统计学意义(均P<0.05);两组上述各指标与治疗前比较,差异均有统计学意义(P<0.05或P<0.01)。结论:步长脑心通胶囊对老年冠心病患者的血脂和血液流变学水平具有理想的调节作用,作用确切,恢复较快,临床上建议进一步推广应用。

    [关键词] 步长脑心通胶囊;老年;冠心病;高血脂;临床疗效

    [中图分类号] R541.4 [文献标识码] B [文章编号] 1673-7210(2011)12(a)-186-02

    Clinical effect of Buchangnaoxintong Capsule in the treatment of coronary heart disease patients with hyperlipidemia

    WU Jiehong

    The Center Hospital of Panyu District, Guangdong Province, Guangzhou 511400, China

    [Abstract] Objective: To explore the clinical effect of Buchangnaoxintong Capsule in the treatment of coronary heart disease patients with hyperlipidemia. Methods: 100 patients in our hospital from January 2008 to April 2011 were divided into two groups randomly. 50 patients in the control group were treated with conventional therapy, 50 patients in the observation group were treated with Buchangnaoxintong Capsule on the base of control group. The level change of TG, CHOL, HDL-C, LDL-C, Apo-A1, Apo-B before treatment and 4-week after treatment of the two groups were compared. Results: 4-week after treatment, TG[(1.74±0.45)mmol/L vs (2.33±1.02)mmol/L], CHOL[(6.34±0.58)mmol/L vs (7.57±2.37)mmol/L], LDL[(2.36±0.32)mmol/L vs (2.99±0.79)mmol/L], Apo-A1[(1.35±0.67)mmol/L vs (1.59±0.78)mmol/L], Apo-B [(1.57±0.37)mmol/L vs (3.08±1.09)mmol/L] of the two groups were compared, those in the observation group were lower than those in the control group, and there were significant differences between the two groups (all P<0.05). There were significant differences of the indexes above between before and after treatment of the two groups (P<0 ......

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