超声内镜在胃癌术前分期检查中的应用价值(1)
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[摘要] 目的:探讨超声胃镜在胃癌术前分期检查中的应用价值。方法:对78例胃癌患者行术前超声胃镜检查及TNM分期,与术后病理检查结果比较并计算准确率。结果:超声内镜对胃癌浸润深度检测与术后病理检查相符70例,准确率为89.7%,对胃癌淋巴结转移检测与术后病理检查相符59例,准确率为75.6%。结论:超声胃镜对胃癌的TNM分期有较大的临床应用价值。
[关键词] 超声胃镜;胃肿瘤;TNM分期
[中图分类号] R735.2 [文献标识码] B [文章编号] 1673-7210(2011)12(b)-168-02
Clinical study of endoscopic ultrasound in gastric cancer preparation staging
YANG Chi1, HUANG Mei1, PENG Lidong1, DOU Liqiong1, HU Xiaozhen2
1.Department of Special Medical Service, the Four Hundred and Twenty-Two Hospital of PLA, Guangdong Province, Zhanjiang 524000, China;2.Department of Special Medical Service, the three hundred and three Hospital of PLA, Nanning,Guangxi Zhuang Autoumous Region, Nanning 530021, China
[Abstract] Objective: To investigate the application of the endoscopic ultrasound (EUS) examination in the preoperative staging of gastric cancer. Methods: 78 patients with gastric cancer were assigned to preoperative EUS examination and TNM staging, which were compared with postoperative pathological examination results to calculate the accuracy. Results: Compared with pathological staging, 70 cases of T staging and 59 cases of N staging assigned to EUS were consistent, and the accuracy of which were 89.7% and 75.6%, respectively. Conclusion: The endoscopic ultrasound for TNM staging of gastric cancer is of greater clinical value.
[Key words] Ultrasound gastroscopy; Gastric cancer; TNM staging
胃癌是临床常见的恶性肿瘤,目前仍采取以手术为主的综合治疗。肿瘤的TNM分期是采取何种手术方案的主要依据。超声内镜结合了内镜与超声检查的优势,可较好地判断肿瘤浸润深度及淋巴结转移情况[1]。本文回顾性分析了78例经超声内镜检查的胃癌患者的临床资料,探讨其在胃癌术前分期检查中的诊断价值。
1资料与方法
1.1 一般资料
78例经活检证实为胃癌的患者均行超声内镜检查,其中,男59例,女19例,年龄28~71岁,平均(55.6±8.3)岁。患者在行超声内镜检查1周后行胃癌根治术或姑息性手术治疗。按病变部位:贲门胃底11例,胃体13例,胃角16例,胃窦28例,弥漫浸润性10例。术后病理主要为腺癌,其中,低分化癌21例,印戒细胞癌9例。
1.2 方法
超声内镜为日本奥林巴斯公司生产UMIR型腔内微型超声探头,频率为7.5、12.0、20.0 MHz。检查前准备同胃镜,开始前15 min服二甲基硅油5 ml,用4%利多卡因对咽峡部位作喷雾麻醉,超声内镜进入胃腔后吸净胃内容物,在胃镜检查发现病灶的部位注入脱气水500~800 ml,立即行超声检查,对不易蓄水的部位采取变换体位的方法注水检查。扫描并记录病变范围及浸润深度,依次探查胰、脾及脾门淋巴结,左肝、肝门区淋巴结,胃网膜左、右淋巴结,胃左、右淋巴结,腹腔淋巴结,贲门淋巴环及隆突下淋巴结。
1.3 TNM分期标准[2]
T1:肿瘤侵及黏膜和(或)黏膜肌或黏膜下层;T2:肿瘤侵及肌层或浆膜下;T3:肿瘤侵透浆膜;T4:肿瘤侵犯临近结构或经腔内扩展至食管、十二指肠。N0:无淋巴结转移;N1:淋巴结转移仅限于肿瘤边缘3 cm内;N2:淋巴结转移超出肿瘤边缘3 cm外。
1.4 统计学方法
以术后病理为金标准,计算超声内镜诊断准确率。
2 结果
2.1 超声内镜对胃癌浸润深度的检测
在78例胃癌手术患者中 ......
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