早发型重度子痫前期的临床特点及围生结局(1)
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[摘要] 目的 探讨早发型重度子痫前期的临床特点及期待治疗围生结局的影响。 方法 回顾性分析我院2002年10月~2010年10月收治的早发型重度子痫前期170例，根据发病孕周不同分成三组：A组(28周≤孕周<30周)25例，B组(30周≤孕周<32周)63例，C组(32周≤孕周<34周)82例，比较三组间期待治疗及围生儿结局。 结果 ①不同发病孕周妊娠并发症(肝肾功能损害、胎盘早剥、HELLP综合征、心衰肺水肿、视网膜病变)比较差异无统计学意义(P > 0.05)；②不同发病孕周期待治疗时间比较差异有统计学意义(P < 0.05)，A组>B组>C组，即随着发病孕周延长，期待治疗时间缩短。 结论 不同早发型重度子痫的发病孕周对妊娠并发症无明显影响，发病孕周越大，其期待治疗时间越短，孕32周之前发病的重度子痫前期围生儿死亡率及新生儿窒息率明显高于32周后发病者。
[关键词] 早发型重度子痫前期；并发症；围生结局
[中图分类号] R714.24+5 [文献标识码] A [文章编号] 1673-7210(2012)02(a)-0034-02
Perinatal outcomes and clinical features in early onset severe preeclampsia
LING Shaoyun CHENG Yanjun WU Xueqin
Department of Obstetrics and Gynecology, Longgang Central Hospital of Shenzhen City, Guangdong Province, Shenzhen 518116, China
[Abstract] Objective To explore the impact of expectant treatment on the perinatal infantile outcome and clinical features in early onset severe preeclampsia (ES2PE). Methods 170 cases with early onset severe preeclampsia admitted to the hospital from October 2002 to October 2010 were analyzed retrospectively, then they were divided into three groups according to onset gestational weeks: group A (28 weeks≤gestational weeks<30 weeks) 25 cases, group B (30 weeks≤gestational weeks<32 weeks) 63 cases, group C (32 weeks≤gestational weeks<34 weeks) 82 cases, the curative effects of expectant treatment and perinatal outcomes in the three groups were compared. Results ①There was no significant difference in incidence of maternal complications ( liver and kidney function damage, placental abruption, HELLP syndrome, heart failure with pulmonary edema, retinal lesions ) among the three groups ( P > 0.05 ); ②there was significant difference in expectant treatment time among the three groups (P < 0.05), group A > group B > group C, the expectant treatment were shorter with the onset of gestational week increased. Conclusion Different gestational age of early onset severe preeclampsia has no significant effect on complications of pregnancy, the greater the gestational age is, the shorter the expected treatment time become, the perinatal mortality and neonatal asphyxia rate of severe preeclampsia occurred before 32 weeks is higher than that occurred after 32 weeks ......
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