微创穿刺对高血压脑出血疗效及预后的影响(1)
[摘要] 目的 探讨微创穿刺对高血压脑出血疗效及预后的影响。 方法 选取我院2009年12月~2010年5月收治的50例高血压脑出血患者为研究对象,其中,25例采用微创穿刺治疗(微创组),25例采用保守方法治疗(对照组),比较两组患者的疗效及预后情况。 结果 微创组的血肿、水肿改善情况及疗效显著优于对照组(P < 0.05),且微创组的再出血率、生活能力及神经缺损程度显著优于对照组(P < 0.05)。 结论 微创穿刺治疗高血压脑出血创伤小,疗效肯定,可显著改善患者预后,值得临床推广。
[关键词] 微创穿刺;高血压脑出血;疗效;预后
[中图分类号] R743.34[文献标识码] A[文章编号] 1673-7210(2012)03(c)-0050-02
The influence of minimally invasive aspiration on the curative effect and prognosis of hypertensive cerebral hemorrhage
, 百拇医药
ZHOU Rulan
Department of Neurology, the People's Hospital of Xiangzhou District in Xiangyang City, Hubei Province, Xiangyang441000, China
[Abstract] Objective To investigate the influence of minimally invasive aspiration on the curative effect and prognosis of hypertensive cerebral hemorrhage. Methods 50 cases of patients with hypertensive cerebral hemorrhage in our hospital from December 2009 to May 2010 as the research object were selected, of whom 25 cases were treated with minimally invasive surgery (minimally invasive group), 25 cases were treated with conservative treatment (control group). The clinical curative effect and prognosis of the two groups were compared. Results the curative effect and improvement of hematoma and edema in the minimally invasive group were significantly better than those in the control group (P < 0.05). The rate of re-bleeding, life skill and nerve defect degree in the minimally invasive group were significantly better than those in the control group (P < 0.05). Conclusion Minimally invasive aspiration in treatment of hypertensive cerebral hemorrhage has small trauma, better curative effect, which can improve prognosis significantly. It is worthy of clinical application.
, 百拇医药
[Key words] Hypertensive cerebral hemorrhage; Minimally invasive; Curative effect; Prognosis
高血压脑出血是神经科的危重病症,致残率和致死率较高。微创穿刺治疗脑出血具有创伤小、血肿清除彻底、伤口愈合快、费用低廉、操作简便等优点[1],被广泛应用于治疗颅内血肿。本研究旨在探讨微创穿刺对高血压脑出血疗效及预后的影响,以期为高血压脑出血早期治疗方法提供循证依据。
1 资料与方法
1.1 一般资料
选取我院2009年12月~2010年5月收治的50例高血压脑出血患者为研究对象,均符合1995年第四届全国脑血管病学术会议制订的高血压脑出血诊断标准,所有病例均行头颅计算机断层扫描(CT)检查明确出血部位,并排除严重的心、肝、肾等疾病或功能衰竭、颅内及全身感染和凝血机制障碍者,所有病例均未破入脑室,急性发病在6~72 h内;首次发病且以往无神经功能缺损。50例患者中男22例,女28例,年龄43~75岁,平均(57.2±5.1)岁;发病时间< 72 h,出血部位:基底节区33例,丘脑8例,脑叶6例,小脑3例;出血量为35~100 mL,平均(45.9±12.1)mL。将患者按照治疗方法的不同分为微创组和对照组,每组各25例,两组患者一般资料比较,差异无统计学意义(P > 0.05),具有可比性。
, 百拇医药
1.2 治疗方法
对照组:采用保守治疗方法,即常规神经内科治疗方法,给予速尿、甘露醇、保护脑细胞、调整血压、预防及处理并发症等内科治疗。微创组:采用微创穿刺治疗,具体方法为患者取卧位,采用CT标志物定位法,以出血量最多、血肿最接近颅骨的CT层面为穿刺点,避开大动脉血管和主要功能区的位置,选择合适长度的YL-1型穿刺针,局麻锥颅钻孔后,用导丝引导内径3.5 mm 硅胶管直接穿刺血肿,接引流管后退出针芯,进行抽吸及冲洗,遇到阻力时,用震荡手法制造工作空间。第1次清除血肿量的20%~40%,一般用生理盐水注入2~5 WU尿激酶,夹闭引流管2 h后开放引流,循环冲洗至冲洗流出液呈淡红色后停止冲洗,根据血肿排除量及复查CT结果决定冲洗次数和引流时间,观察患者意识状态及肢体活动等体征变化。术后复查CT,无血肿时拔针,局部缝合并无菌加压包扎。
1.3 评价指标
选择治疗30 d为治疗终点,比较两组患者的血肿平均大小、水肿平均大小及疗效。随访3~6个月,比较两组生活能力(ADL)、神经缺损程度(NDF)情况。疗效判定标准分为4个阶段:基本痊愈、显著进步、进步、恶化[3],并以治愈、显著进步和进步计算总有效。采用第四次全国脑血管病学术会议通过的脑出血神经功能缺损程度评分标准评定治疗前后患者神经功能缺损情况,采用Barthel指数评定ADL。
1.4 统计学方法
采用SPSS 13.0统计学软件进行数据分析,计量资料数据用均数±标准差(x±s)表示,两组间比较采用t检验;计数资料用率表示,组间比较采用χ2检验,以P < 0.05为差异有统计学意义。
2 结果
2.1 两组患者血肿、水肿的改善及疗效比较, 百拇医药(周如兰)
[关键词] 微创穿刺;高血压脑出血;疗效;预后
[中图分类号] R743.34[文献标识码] A[文章编号] 1673-7210(2012)03(c)-0050-02
The influence of minimally invasive aspiration on the curative effect and prognosis of hypertensive cerebral hemorrhage
, 百拇医药
ZHOU Rulan
Department of Neurology, the People's Hospital of Xiangzhou District in Xiangyang City, Hubei Province, Xiangyang441000, China
[Abstract] Objective To investigate the influence of minimally invasive aspiration on the curative effect and prognosis of hypertensive cerebral hemorrhage. Methods 50 cases of patients with hypertensive cerebral hemorrhage in our hospital from December 2009 to May 2010 as the research object were selected, of whom 25 cases were treated with minimally invasive surgery (minimally invasive group), 25 cases were treated with conservative treatment (control group). The clinical curative effect and prognosis of the two groups were compared. Results the curative effect and improvement of hematoma and edema in the minimally invasive group were significantly better than those in the control group (P < 0.05). The rate of re-bleeding, life skill and nerve defect degree in the minimally invasive group were significantly better than those in the control group (P < 0.05). Conclusion Minimally invasive aspiration in treatment of hypertensive cerebral hemorrhage has small trauma, better curative effect, which can improve prognosis significantly. It is worthy of clinical application.
, 百拇医药
[Key words] Hypertensive cerebral hemorrhage; Minimally invasive; Curative effect; Prognosis
高血压脑出血是神经科的危重病症,致残率和致死率较高。微创穿刺治疗脑出血具有创伤小、血肿清除彻底、伤口愈合快、费用低廉、操作简便等优点[1],被广泛应用于治疗颅内血肿。本研究旨在探讨微创穿刺对高血压脑出血疗效及预后的影响,以期为高血压脑出血早期治疗方法提供循证依据。
1 资料与方法
1.1 一般资料
选取我院2009年12月~2010年5月收治的50例高血压脑出血患者为研究对象,均符合1995年第四届全国脑血管病学术会议制订的高血压脑出血诊断标准,所有病例均行头颅计算机断层扫描(CT)检查明确出血部位,并排除严重的心、肝、肾等疾病或功能衰竭、颅内及全身感染和凝血机制障碍者,所有病例均未破入脑室,急性发病在6~72 h内;首次发病且以往无神经功能缺损。50例患者中男22例,女28例,年龄43~75岁,平均(57.2±5.1)岁;发病时间< 72 h,出血部位:基底节区33例,丘脑8例,脑叶6例,小脑3例;出血量为35~100 mL,平均(45.9±12.1)mL。将患者按照治疗方法的不同分为微创组和对照组,每组各25例,两组患者一般资料比较,差异无统计学意义(P > 0.05),具有可比性。
, 百拇医药
1.2 治疗方法
对照组:采用保守治疗方法,即常规神经内科治疗方法,给予速尿、甘露醇、保护脑细胞、调整血压、预防及处理并发症等内科治疗。微创组:采用微创穿刺治疗,具体方法为患者取卧位,采用CT标志物定位法,以出血量最多、血肿最接近颅骨的CT层面为穿刺点,避开大动脉血管和主要功能区的位置,选择合适长度的YL-1型穿刺针,局麻锥颅钻孔后,用导丝引导内径3.5 mm 硅胶管直接穿刺血肿,接引流管后退出针芯,进行抽吸及冲洗,遇到阻力时,用震荡手法制造工作空间。第1次清除血肿量的20%~40%,一般用生理盐水注入2~5 WU尿激酶,夹闭引流管2 h后开放引流,循环冲洗至冲洗流出液呈淡红色后停止冲洗,根据血肿排除量及复查CT结果决定冲洗次数和引流时间,观察患者意识状态及肢体活动等体征变化。术后复查CT,无血肿时拔针,局部缝合并无菌加压包扎。
1.3 评价指标
选择治疗30 d为治疗终点,比较两组患者的血肿平均大小、水肿平均大小及疗效。随访3~6个月,比较两组生活能力(ADL)、神经缺损程度(NDF)情况。疗效判定标准分为4个阶段:基本痊愈、显著进步、进步、恶化[3],并以治愈、显著进步和进步计算总有效。采用第四次全国脑血管病学术会议通过的脑出血神经功能缺损程度评分标准评定治疗前后患者神经功能缺损情况,采用Barthel指数评定ADL。
1.4 统计学方法
采用SPSS 13.0统计学软件进行数据分析,计量资料数据用均数±标准差(x±s)表示,两组间比较采用t检验;计数资料用率表示,组间比较采用χ2检验,以P < 0.05为差异有统计学意义。
2 结果
2.1 两组患者血肿、水肿的改善及疗效比较, 百拇医药(周如兰)