[摘要] 近年来以尿道前列腺部为系统，进行治疗下尿路症状药物的研究越来越盛行，其中,以尿道α1受体的研究最多，对于其他受体文献则很少有报道。本文系统阐述了常见实验动物及人尿道前列腺部受体分布、功能和受体表达的调节等状况，对于寻找诊治下尿路症状的新药，深入理解下尿路症状发病机制，有重大意义。

    [关键词] 尿道；α1A受体；前列腺增生；下尿路症状

    [中图分类号] R365.694 [文献标识码] A [文章编号] 1673-7210(2012)04(a)-0014-03

    Differences and pharmacological significance of tension-regulating receptors in prostatic urethra of common experimental animals

    SU Xin WU Jianhui SUN Zuyue

    Department of Pharmacology and Toxicology, Shanghai Institute of Planned Parenthood Research National Evaluation Center for the Toxicology of Fertility Regulation Drugs, Shanghai 200032, China ......