消化道肿瘤体外化疗药物敏感性与临床特征的相关性(2)
总之，体外肿瘤药敏试验可以判定各化疗药对肿瘤组织的敏感性，为临床标准化化疗用药及个体化化疗提供依据，其作用机制独特，对消化道肿瘤的辅助化疗有一定帮助。
[参考文献]
[1] 魏嘉，刘宝瑞.DNA修复基因的单核苷酸多态性与铂类药物抵抗研究进展[J].中华肿瘤杂志，2006，28(3)：161-163.
[2] 王立峰，刘宝瑞.药物遗传学和药物基因组学在肿瘤治疗中的应用[J].世界华人消化杂志，2006，14(3)：318-323.
[3] Andre J，Boni C，Mounedji B，et al. Oxaliplatin，fluorouracil and leucovorin as adjuvant treatment for colon cancer [J]. N Eng J Med，2004，350(23)：2343-2351.
[4] Folkesson J，Birgisson H，Pahalman I，et al. Swedish Rectal Cancer Trial：long lasting benefits from radiotherapy on survival and local recurrence rate [J]. J Clin Oncol，2005，23(24)：5644-5650.
[5] Bosset JF，Calais G，Mineur L，et al. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer：preliminary resμlts-EORTC 22921[J]. J Clin Oncol，2005，23(24)：5620-5627.
[6] Park DJ，Lenz L. Determinants of chemosensitivity in gastric cancer [J]. Curt Opin Pharmaeol，2006，6(4)：337-339.
[7] Sadighi S，Mohagheghl MA，Montazeri A，et al. Quality of life in patients with advanced gastric cancer：a randomized trial comparing docetaxel，cisplatin，5-FU (TCF)with epirubicin，cisplatin，5-FU(ECF) [J]. BMC Cancer，2006，6：274-278.
[8] Folkesson J，Birgisson H，Pahalman I，et al. Swedish Rectal Cancer Trial：long lasting benefits from radiotherapy on survival and local recurrence rate [J]. J Clin Oncol，2005，23(24)：5644-5650.
(收稿日期：2012-01-13 本文编辑：程铭), http://www.100md.com(韩云国)
[参考文献]
[1] 魏嘉，刘宝瑞.DNA修复基因的单核苷酸多态性与铂类药物抵抗研究进展[J].中华肿瘤杂志，2006，28(3)：161-163.
[2] 王立峰，刘宝瑞.药物遗传学和药物基因组学在肿瘤治疗中的应用[J].世界华人消化杂志，2006，14(3)：318-323.
[3] Andre J，Boni C，Mounedji B，et al. Oxaliplatin，fluorouracil and leucovorin as adjuvant treatment for colon cancer [J]. N Eng J Med，2004，350(23)：2343-2351.
[4] Folkesson J，Birgisson H，Pahalman I，et al. Swedish Rectal Cancer Trial：long lasting benefits from radiotherapy on survival and local recurrence rate [J]. J Clin Oncol，2005，23(24)：5644-5650.
[5] Bosset JF，Calais G，Mineur L，et al. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer：preliminary resμlts-EORTC 22921[J]. J Clin Oncol，2005，23(24)：5620-5627.
[6] Park DJ，Lenz L. Determinants of chemosensitivity in gastric cancer [J]. Curt Opin Pharmaeol，2006，6(4)：337-339.
[7] Sadighi S，Mohagheghl MA，Montazeri A，et al. Quality of life in patients with advanced gastric cancer：a randomized trial comparing docetaxel，cisplatin，5-FU (TCF)with epirubicin，cisplatin，5-FU(ECF) [J]. BMC Cancer，2006，6：274-278.
[8] Folkesson J，Birgisson H，Pahalman I，et al. Swedish Rectal Cancer Trial：long lasting benefits from radiotherapy on survival and local recurrence rate [J]. J Clin Oncol，2005，23(24)：5644-5650.
(收稿日期：2012-01-13 本文编辑：程铭), http://www.100md.com(韩云国)