双骨汤对中老年骨关节炎临床疗效分析(1)
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[摘要] 目的 探讨双骨汤治疗中老年骨性关节炎的临床疗效。 方法 选择21例膝骨性关节炎患者为治疗组，连续服用双骨汤，另选取21例健康者为对照组，比较两组临床总有效率及检测尿环磷酸酰酸胺CTX-Ⅱ和尿肌酐的变化。 结果 治疗组治疗后总有效率为90.47%，与治疗前(52.38%)比较差异有统计学意义(P < 0.05)；治疗组患者尿CTX-Ⅱ检测值明显升高，与对照组比较差异有统计学意义(P < 0.05)。 结论 双骨汤能改善患者的临床症状和膝关节功能，可缓解膝关节软骨破坏，具有治疗作用。
[关键词] 骨关节炎；双骨汤；有效率；尿Ⅱ型胶原羧基端肽
[中图分类号] R684.3 [文献标识码] A [文章编号] 1673-7210(2012)08(a)-0112-03
The clinical efficiency of Shuanggu Decoction in the treatment of elderly patients with osteoarthritis
CHEN Ruijian1 CHEN Guopeng2 HUANG Xiaohong1 LIU Bohao1 LIU Yanxin1 LI Zesen1 HUANG Bincheng1 ZHI Yuesen1 TU Pingsheng3▲
1.Department of Orthopedics and Traumatology, Traelitional Chinese Medicine Hospital of Panyu District in Guangzhou City, Guangdong Province, Guangzhou 511400, China; 2.Department of Orthopedic, Shawan Town Hospital of Panyu District in Guangzhou City, Guangdong Province, Guangzhou 511483, China; 3.Department of Orthopedic in Fourth District Traelitional Chinese Medicine Hospital of Panyu District in Guangzhou City, Guangdong Province, Guangzhou 511400, China
[Abstract] Objective To discuss the clinical efficiency of Shuanggu Decoction in the treatment of elderly patients with osteoarthritis. Methods 21 osteoarthritis patients were selected as treatment group, who were given Shuanggu Decoction, another 21 healthy people were selected as control group. The clinical therapy and the change of the urine Cyclophosphamide CTX-Ⅱ and urine creatinine were compared. Results The total effective rate was 90.47% after therapy, it had statistical significance compared with before treatment (P < 0.05) ......
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