895例药品不良反应报告分析(1)
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[摘要] 目的 了解和探索我院药品不良反应(ADR)发生规律及特点，为临床安全用药提供参考。 方法 对我院2009年1月～2010年12月收集上报的895例ADR报告，按照患者性别、年龄、给药途径、药物种类、ADR累及器官或系统及临床表现等进行分类统计与分析。 结果 895例报告中，50岁以上人群所占比例最大，占50.73%；涉及的药品中，以抗菌药物居多，占58.26%；静脉给药方式是引发ADR的重要给药途径，占92.29%；累及器官或系统以皮肤及其附件损伤最为常见，占50.61%。 结论 临床应加强ADR报告和监测工作，规范使用抗菌药物，以减少ADR发生率。
[关键词] 不良反应；药品；安全用药
[中图分类号] R957 [文献标识码] C [文章编号] 1673-7210(2012)08(a)-0121-03
Analysis of 895 cases of adverse drug reaction reports
WANG Yongtian JIANG Yao SUN Jing
The Affiliated Zibo City First Hospital of Weifang Medical University, Shandong Province, Zibo 255200, China
[Abstract] Objective To understand and explore the regularity and characteristics of adverse drug reactions (ADR) in our hospital and provide reference for clinical medication safety. Methods 895 cases of ADR reports in our hospital from January 2009 to December 2010 were collected, the gender, age, route of administration, drug type, ADR involving organ or system, clinical manifestations of patients were classified for statistical analysis. Results Out of the 895 cases of reports, the population of over 50 years old accounted for the major of 50.73%; of the involved drugs, antimicrobial agents accounted for the major of 58.26%; intravenous drug administration was an important route of administration causing ADR, which accounted for 92.29%; of the involving organ or system, skin and its accessories accounted for the major of 50.61%. Conclusion Clinical ADR reporting and monitoring should be strengthened and using of antimicrobial drugs should be standardized in order to reduce the incidence of ADR.
[Key words] Adverse reactions; Drug; Medication safety ......
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