腹膜假黏液瘤7例临床分析(2)
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国外目前的先进治疗手段:①Pillai等[20]通过对腹膜假黏液瘤黏液性腹水的研究,认为溶黏蛋白是一种可处理黏液性腹水的药物,已有证据表明,抗坏血酸(0.1%~0.2%)和过氧化氢(0~3%)协同作用下可溶解黏液性腹水,将该类药物作为黏液溶解剂,是今后治疗黏液性腹水的可行性方案[21]。②腹膜假黏液瘤最易出现的并发症是大量黏液性腹水积聚而造成的肠梗阻,并最终导致死亡,Choudry等[22]实验研究使用消炎药、地塞米松、西乐葆能抑制细胞外黏液的产生,可能会降低腹膜假黏液瘤并发症的发生,提高无病间隔,并降低肿瘤细胞减灭术的次数。
3.4 复发的评估
Chua等[23]研究CEA、CA199、CA125的升高可能是腹膜假黏液瘤患者术后早期复发(≤12个月)的一个重要因素。本组中3例CEA升高,1例并CA199、CA125均升高,其中2例均于早期复发。
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