[摘要] 血-脊髓屏障(BSCB)是血液循环和脊髓组织之间的生理和代谢物质扩散的屏障。BSCB的破坏是脊髓缺血再灌注损伤(SCIRI)的重要病理改变之一，在SCIRI的发生发展中起关键作用。药物、缺血预处理等可通过保护BSCB完整性减轻SCIRI。远端缺血预处理(RIPC)可对SCIRI产生保护作用，但其内在机制仍有待阐明。本文就BSCB的形态结构与功能、SCIRI后BSCB损伤的机制及RIPC对SCIRI的保护作用作一综述。

    [关键词] 脊髓缺血；再灌注损伤；缺血预处理；血-脊髓屏障

    [中图分类号] R651.2 [文献标识码] A [文章编号] 1673-7210(2016)03(c)-0068-05

    [Abstract] The blood-spinal cord barrier (BSCB) is the physiological and metabolic substance diffusion barrier between blood circulation and spinal cord tissues. The disruption of the BSCB is one of the important pathological changes in the course of spinal cord ischemia reperfusion injury (SCIRI) ......