白细胞介素—8与肿瘤的研究进展(1)
[摘要] 白细胞介素-8(IL-8)是一细胞来源较为丰富的细胞因子,属趋化因子CXC亚家族成员之一。最初研究表明,IL-8在调节细胞生长与分化、炎性反应、免疫应答、机体防御损伤及修复等过程中起着重要作用。最新研究发现,IL-8在肿瘤发生发展中亦发挥重要作用。本文简述了IL-8的血清表达及其临床意义,并从多角度对IL-8与肿瘤易感性、肿瘤血管生长、肿瘤发展演进及肿瘤耐药之间的关系展开分析,分析表明IL-8与肿瘤最初发生到最终浸润转移及临床化疗之间关系密切。因此,对其进行深入研究有望给肿瘤临床化疗带来新的突破,为肿瘤靶向治疗提供新的思路。
[关键词] IL-8;肿瘤;研究进展
[中图分类号] R73 [文献标识码] A [文章编号] 1673-7210(2016)09(b)-0033-06
[Abstract] Interleukin-8 (IL-8) is a cytokine which has an abundant source of cells. And it is also a member of the CXC subfamily of chemokines. Initial studies indicate that IL-8 plays an important role in regulating cell growth ......
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[关键词] IL-8;肿瘤;研究进展
[中图分类号] R73 [文献标识码] A [文章编号] 1673-7210(2016)09(b)-0033-06
[Abstract] Interleukin-8 (IL-8) is a cytokine which has an abundant source of cells. And it is also a member of the CXC subfamily of chemokines. Initial studies indicate that IL-8 plays an important role in regulating cell growth ......
您现在查看是摘要页,全文长 4888 字符。