缺氧诱导因子与肾性贫血(6)
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(收稿日期:2016-08-01 本文編辑:张瑜杰), 百拇医药(刘珊 丁国华 王惠明)
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[34] Brigandi RA,Johnson B,Oei C,et al. A Novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor(GSK12 78863)for Anemia in CKD:A 28-Day,Phase 2A Randomized Trial [J]. Am J Kidney Dis,2016,67(6):861-871.
[35] Flamme I,Oehme F,Ellinghaus P,et al. Mimicking hypoxia to treat anemia:HIF-stabilizer BAY 85-3934(Molidustat)stimulates erythropoietin production without hypertensive effects [J]. PLoS One,2014,9(11):e111838.
[36] Maxwell PH,Eckardt KU. HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond [J]. Nat Rev Nephrol,2016,12(3):157-168.
[37] Schmid H,Jelkmann W. Investigational therapies for renal disease-induced anemia [J]. Expert Opin Investig Drugs,2016,25(8):901-916.
(收稿日期:2016-08-01 本文編辑:张瑜杰), 百拇医药(刘珊 丁国华 王惠明)