[摘要] 动脉粥样硬化(AS)是一种随年龄不断增长、以中老年人为主要发病人群的自身免疫性疾病。自噬是由溶酶体介导的降解细胞内受损细胞器或蛋白质的代谢过程。基于免疫介导的细胞自噬在AS形成、发展中的重要作用以及补肾中药复方有效干预治疗AS的前期研究结果，现拟从细胞自噬角度深入探讨补肾中药复方通过细胞自噬途径干预AS的研究策略。

    [关键词] 动脉粥样硬化；衰老；免疫；自噬；补肾中药复方

    [中图分类号] R285 [文献标识码] A [文章编号] 1673-7210(2017)07(a)-0077-04

    [Abstract] Atherosclerosis (AS) is an autoimmune disease that grows with age and is predominantly in the elderly. Autophagy is a lysosomal-mediated process for the degradation of intracellularly damaged organelles or proteins. Based on the important role of immune-mediated autophagy in the AS formation and development and the effect of compound Chinese Medicine for reinforcing kidney on intervention of AS. This paper intends to explore the research strategy of compound Chinese Medicine for reinforcing kidney by interfering with AS by autophagy pathway.

    [Key words] Atherosclerosis； Aging； Immune； Autophagy； Compound Chinese medicine for reinforcing kidney

    动脉粥样硬化(Atherosclerosis ......