神经介入治疗缺血性脑血管疾病的近、远期临床效果(1)
[摘要] 目的 探討神经介入治疗缺血性脑血管疾病的近、远期临床效果及对神经功能的改善作用。 方法 选择2015年3月～2016年6月新疆维吾尔自治区人民医院134例缺血性脑血管病患者，按随机数字表法随机分为对照组和研究组，各67例，对照组进行常规治疗，研究组应用神经介入进行治疗。评估治疗后1个月病变血管再通情况和并发症发生率，患者病变血管收缩期峰流速(Vs)、舒张末期流速(Vd)，评估治疗前后神经功能缺损状况(NIHSS评分)、生活自理能力及缺血性脑血管病事件复发率、病死率。 结果 研究组治疗后再通率高于对照组；研究组并发症总发生率低于对照组，差异有统计学意义(P < 0.05)；研究组治疗后Vs和Vd均低于对照组，差异有统计学意义(P < 0.05)；两组治疗后NIHSS评分均低于治疗前，且研究组治疗后1、3、6、12个月结果均低于对照组，差异有统计学意义(P < 0.05)；研究组治疗后6、12个月ADL评分均低于对照组，差异有统计学意义(P < 0.05)；研究组患者出现复发和病死总发生率低于对照组，差异有统计学意义(P < 0.05)。 结论 神经介入治疗缺血性脑血管疾病，近期能显著提高病变血管再通率和神经功能，降低并发症发生率，远期能够提高患者神经功能和日程生活能力，显著降低患者复发率和病死率。
[关键词] 缺血性脑血管疾病；神经介入治疗；临床效果；并发症
[中图分类号] R743 [文献标识码] A [文章编号] 1673-7210(2018)03(a)-0070-04
[Abstract] Objective To explore the clinical effect of nerve intervention therapy in the treatment of short-term and long-term ischemic cerebrovascular diseases. Methods One hundred and thirty-four patients with ischemic cerebrovascular disease from March 2015 to June 2016 in People′s Hospital of Xinjiang Uygur Autonomous Region were selected and divided into control group and study group by random number table， with 67 cases in each group. The control group received routine treatment and the study group received neural neurological therapy. One month after treatment， the incidence of recanalization， the incidence of complications， the peak systolic velocity (Vs) and end-diastolic velocity (Vd) of the patients were evaluated. The neurological deficit， life ability and the relapse and mortality of ischemic cerebrovascular disease of patients before and after treatment were assessed. Results The recanalization rate of the study group was higher than that of the control group， the total complication rate of the study group was lower than that of the control group， the difference was statistically significant (P < 0.05). The Vs and Vd of the study group were lower than those of the control group， the differences were statistically significant (P < 0.05). After treatment， the scores of NIHSS were lower than before in two groups， the study group after 1， 3， 6 and 12 months treatment were lower than those of the control group， the differences were statistically significant (P < 0.05). The ADL scores of the study group after 6 and 12 months treatment were lower than those of control group， the difference was statistically significant (P < 0.05). The total incidence of recurrence and death of the study group were lower than that in the control group， the differences were statistically significant (P < 0.05). Conclusion Nerve intervention therapy for patients with ischemic cerebrovascular disease can significantly improve the vascular recanalization rate and neurological function， reduce the incidence of complications in a short-term. It can significantly improve the patient's neurological function and the life ability， reduce the recurrence rate and mortality in long-term., 百拇医药(祖合热阿依·牙合甫 党辉 王成凤 陈伟)
[关键词] 缺血性脑血管疾病；神经介入治疗；临床效果；并发症
[中图分类号] R743 [文献标识码] A [文章编号] 1673-7210(2018)03(a)-0070-04
[Abstract] Objective To explore the clinical effect of nerve intervention therapy in the treatment of short-term and long-term ischemic cerebrovascular diseases. Methods One hundred and thirty-four patients with ischemic cerebrovascular disease from March 2015 to June 2016 in People′s Hospital of Xinjiang Uygur Autonomous Region were selected and divided into control group and study group by random number table， with 67 cases in each group. The control group received routine treatment and the study group received neural neurological therapy. One month after treatment， the incidence of recanalization， the incidence of complications， the peak systolic velocity (Vs) and end-diastolic velocity (Vd) of the patients were evaluated. The neurological deficit， life ability and the relapse and mortality of ischemic cerebrovascular disease of patients before and after treatment were assessed. Results The recanalization rate of the study group was higher than that of the control group， the total complication rate of the study group was lower than that of the control group， the difference was statistically significant (P < 0.05). The Vs and Vd of the study group were lower than those of the control group， the differences were statistically significant (P < 0.05). After treatment， the scores of NIHSS were lower than before in two groups， the study group after 1， 3， 6 and 12 months treatment were lower than those of the control group， the differences were statistically significant (P < 0.05). The ADL scores of the study group after 6 and 12 months treatment were lower than those of control group， the difference was statistically significant (P < 0.05). The total incidence of recurrence and death of the study group were lower than that in the control group， the differences were statistically significant (P < 0.05). Conclusion Nerve intervention therapy for patients with ischemic cerebrovascular disease can significantly improve the vascular recanalization rate and neurological function， reduce the incidence of complications in a short-term. It can significantly improve the patient's neurological function and the life ability， reduce the recurrence rate and mortality in long-term., 百拇医药(祖合热阿依·牙合甫 党辉 王成凤 陈伟)