纤维支气管镜早期介入治疗肺炎支原体肺炎合并气道内黏液栓阻塞患儿的临床价值(1)
[摘要] 目的 探讨纤维支气管镜早期介入治疗肺炎支原体肺炎(MPP)合并气道内黏液栓阻塞患儿的临床价值。方法 回顾性分析2015年2月～2017年2月成都市妇女儿童中心医院儿童呼吸科收治的92例MPP合并气道内黏液栓阻塞患兒的临床资料，根据入院行纤维支气管镜介入治疗所对应的病程时间进行分组，其中病程>10 d者为对照组(45例)，病程≤10 d者为观察组(47例)，比较分析两组患儿治疗效果。 结果 观察组热程、住院时间、白细胞恢复正常时间、C-反应蛋白恢复正常时间均明显短于对照组，差异有高度统计学意义(P < 0.01)。治疗后1、2、3个月观察组肺部实变吸收情况优于对照组，差异有统计学意义(P < 0.05)。治疗后1、2、3个月观察组肺不张发生率明显低于对照组，差异有统计学意义(P < 0.05)。 结论 纤维支气管镜早期介入治疗MPP合并气道内黏液栓阻塞患儿，其安全性较好，临床价值高，值得临床推广。
[关键词] 纤维支气管镜;早期介入;肺炎支原体肺炎;气道内黏液栓阻塞
[中图分类号] R725.5 [文献标识码] A [文章编号] 1673-7210(2019)08(c)-0107-04
[Abstract] Objective To investigate the clinical value of early interventional therapy with fiberoptic bronchoscopy in children with Mycoplasma pneumoniae pneumonia (MPP) complicated with airway mucus embolism. Methods Clinical data of 92 MPP children complicated with airway mucus embolism in Department of Children′s Respiratory of Chengdu Women's and Children′s Central Hospital from February 2015 to February 2017 A retrospective， they were grouped according to the course of disease that from admission to fiberoptic bronchoscopy interventional therapy， children with the course of disease more than 10 days were defined as the control group (45 cases) and whose the course of disease less than or equal to 10 days were defined as the observation group (47 cases). The therapeutic effects of the two groups were compared and analyzed. Results The duration of fever， hospitalization， recovery time of white blood cell count and C-reactive protein in the observation group were significantly shorter than those in the control group， the differences were highly statistically significant (P < 0.01). There was statistically significant difference in the proportion of children with 60%-90% pulmonary consolidation absorption area 1， 3 months after treatment (P < 0.05); the pulmonary consolidation absorption areas of children in the observation group 1， 2， 3 months after treatment were better than those in the control group， the differences were statistically significant (P < 0.05). The incidence of atelectasis in the observation group was significantly lower than that in the control group 1， 2， 3 months after treatment， the differences were statistically significant (P < 0.05). Conclusion Early intervention of fiberoptic bronchoscopy in the treatment of MPP patients with airway obstruction with intraairway mucus embolism has a good safety and high clinical value， which is worthy of clinical promotion., 百拇医药(陶沛 夏万敏)
[关键词] 纤维支气管镜;早期介入;肺炎支原体肺炎;气道内黏液栓阻塞
[中图分类号] R725.5 [文献标识码] A [文章编号] 1673-7210(2019)08(c)-0107-04
[Abstract] Objective To investigate the clinical value of early interventional therapy with fiberoptic bronchoscopy in children with Mycoplasma pneumoniae pneumonia (MPP) complicated with airway mucus embolism. Methods Clinical data of 92 MPP children complicated with airway mucus embolism in Department of Children′s Respiratory of Chengdu Women's and Children′s Central Hospital from February 2015 to February 2017 A retrospective， they were grouped according to the course of disease that from admission to fiberoptic bronchoscopy interventional therapy， children with the course of disease more than 10 days were defined as the control group (45 cases) and whose the course of disease less than or equal to 10 days were defined as the observation group (47 cases). The therapeutic effects of the two groups were compared and analyzed. Results The duration of fever， hospitalization， recovery time of white blood cell count and C-reactive protein in the observation group were significantly shorter than those in the control group， the differences were highly statistically significant (P < 0.01). There was statistically significant difference in the proportion of children with 60%-90% pulmonary consolidation absorption area 1， 3 months after treatment (P < 0.05); the pulmonary consolidation absorption areas of children in the observation group 1， 2， 3 months after treatment were better than those in the control group， the differences were statistically significant (P < 0.05). The incidence of atelectasis in the observation group was significantly lower than that in the control group 1， 2， 3 months after treatment， the differences were statistically significant (P < 0.05). Conclusion Early intervention of fiberoptic bronchoscopy in the treatment of MPP patients with airway obstruction with intraairway mucus embolism has a good safety and high clinical value， which is worthy of clinical promotion., 百拇医药(陶沛 夏万敏)